Parkinson’s disease results from the loss of specific nerve cells that produce dopamine, a chemical that is vital for the control of muscles and movement.
Human Immunodeficiency Virus (HIV) infection places an immense burden on global health. The virus causes Acquired Immune Deficiency Syndrome (AIDS) by depleting infection-fighting immune cells.
Allergies are caused by a hyperactive immune system mistakenly responding to external substances such as food, pollen or medications. Allergies impact on quality of life, and in severe cases can be life-threatening.
Melanoma is an aggressive form of skin cancer. The disease can be effectively treated if detected early but is dangerous once it spreads throughout the body.
Cancer will affect 1 in 3 Australians during their lifetime. Although some types of cancer can be cured, for others there are few effective treatments.
Myeloproliferative disorders are serious conditions in which excessive numbers of blood cells are produced. This can interfere with the normal functions of blood.
Blood cancers are abnormally growing cells that arise from cells in the blood system. Leukaemia, lymphoma and myeloma are common types of blood cancer.
We are working to improve the health of people around the world through discovery of the basic mechanisms of disease and by finding and testing solutions to optimise health outcomes.
Healthy development fosters a child's positive growth, focusing on achieving their full intellectual and physical potential, while avoiding long-term health challenges.
Our researchers are using AI and machine learning in many areas of research, including the analysis of complex omics data sets, structural biology, image analysis, and drug discovery.
We are undertaking a program of large randomised controlled trials in rural Bangladesh and Malawi to assess new solutions for anaemia control with the goal of improving maternal and child health.
We are undertaking a program of large randomised controlled trials in rural Bangladesh and Malawi to assess new solutions for anaemia control with the goal of improving maternal and child health.
We are undertaking a program of large randomised controlled trials in rural Bangladesh and Malawi to assess new solutions for anaemia control with the goal of improving maternal and child health.
Olink affinity proteomics is a next-generation technology that quantifies thousands of biologically relevant proteins at low concentration in collections.
The Colonial Foundation Diagnostics Centre is a pioneering research centre established to advance precision diagnosis for diseases that affect millions of Australians.
The Snow Centre for Immune Health is a research centre with a mission to improve the lives of people with immune diseases, using an approach to immune health that's the first of its kind.
Dr Kate McArthur is using cutting edge imaging techniques to understand how DNA is released from mitochondria, a process that has been implicated in the development of autoimmune disease.
WEHI's Centre for Dynamic Imaging is run by an interdisciplinary research team with expertise in biomedical engineering, physics, mathematics and biology.
Advanced microscopy techniques are helping researchers like Iromi Wanigasuriya understand how genes are switched on and off, a process called epigenetic control of gene expression.
Researchers are using multiplexed, 3-dimensional imaging to combine information about cancer cell movement and blood vessel structure to better understand how tumour cells invade other tissues.
Access to the Centre’s suite of imaging technologies has enabled WEHI researcher Dr Andre Samson to discover how the killer protein MLKL exerts its deadly job.
Advanced live-microscopy techniques have become the most effective avenue for studying the interactions between the malaria parasite and the host red blood cell prior to, during, and after infection.
The combination of patient-focused Snow Research Clinics and WEHI’s co-leadership with the Royal Melbourne Hospital means, in the future, discoveries can be rapidly taken out of the lab to benefit patients.
Inflammation is the body’s natural response to infection, disease and tissue damage. However, ongoing or misdirected inflammation underlies many diseases.
Members of the Immunology division are dedicated to finding out how the immune system works and how it might be manipulated to achieve new disease treatments.
We use structural, chemical and molecular biology approaches along with medicinal chemistry and high-throughput screening, to discover new therapeutics.
Scientists in the Bioinformatics and Computational Biology division develop new computational, statistical and AI strategies to interpret the huge amounts of "omics" data generated in biomedical research.
Our division focuses on discovering new medicines through studies of the three-dimensional structure of large biological molecules that are either targets for drugs or potential therapeutic agents.
Sir Neil Hamilton Fairley, together with staff from Melbourne’s abattoirs, examines over 50,000 animals to investigate the prevalence of disease among livestock, including tuberculosis, tapeworm (hydatid) and liver fluke.
Sir Frank Macfarlane Burnet becomes infected with a chicken virus, while researching the relationship between a fowl virus called Newcastle disease (NDV) and influenza.