Lelliott EJ, Naddaf J, Ganio K, Michie J, Wang S, Liu L, Silke N, Ahn A, Ramsbottom KM, Brennan AJ, Freeman AJ, Goel S, Vervoort SJ, Kearney CJ, Beavis PA, McDevitt CA, Silke J, Oliaro J. Intracellular zinc protects tumours from T cell-mediated cytotoxicity. Cell Death & Differentiation. 2024;31(12):10.1038/s41418-024-01369-4
Anderton H, Bandala-Sanchez E, Simpson DS, Rickard JA, Ng AP, Di Rago L, Hall C, Vince JE, Silke J, Liccardi G, Feltham R. Correction to: RIPK1 prevents TRADD-driven, but TNFR1 independent, apoptosis during development. Cell Death & Differentiation. 2024;31(12):10.1038/s41418-024-01401-7
Nordmann TM, Anderton H, Hasegawa A, Schweizer L, Zhang P, Stadler P-C, Sinha A, Metousis A, Rosenberger FA, Zwiebel M, Satoh TK, Anzengruber F, Strauss MT, Tanzer MC, Saito Y, Gong T, Thielert M, Kimura H, Silke N, Rodriguez EH, Restivo G, Nguyen HH, Gross A, Feldmeyer L, Joerg L, Levesque MP, Murray PJ, Ingen-Housz-Oro S, Mund A, Abe R, Silke J, Ji C, French LE, Mann M. Spatial proteomics identifies JAKi as treatment for a lethal skin disease. Nature. 2024;635(8040):10.1038/s41586-024-08061-0
Liu L, Silke J. AXIN2 is a non‐redundant regulator of AXIN1 stability and β‐catenin in colorectal cancer cells. The FEBS Journal. 2024;:10.1111/febs.17336
Wang Y, Liu Z, Si Q, Lu W, Song Y, Jin W, Yang X, Li Z, Hu X, Ding L, Jing Y, Weng P, Yu Q, O’Reilly LA, Silke J, Zhang X, Hu Q, Ni Y. Complex IIa formation and ABC transporters determine sensitivity of OSCC to Smac mimetics. Cell Death & Disease. 2024;15(11):10.1038/s41419-024-07253-w
Nordmann T, Anderton H, Hasegawa A, Schweizer L, Zhang P, Stadler P, Sinha A, Andreas M, Florian R, Maximilian Z, Satoh TK, Saito Y, Gong T, Thielert M, Kimura H, Nguyen H, Levesque M, Murray P, Ingen-Housz-Oro S, Mund A, Abe R, Silke J, Ji C, French LE, Mann M. 720 Cell-type resolved spatial proteomics uncovers a novel actionable therapeutic target in toxic epidermal necrolysis. Journal of Investigative Dermatology. 2024;144(8):10.1016/j.jid.2024.06.736
Chiou S, Al-Ani AH, Pan Y, Patel KM, Kong IY, Whitehead LW, Light A, Young SN, Barrios M, Sargeant C, Rajasekhar P, Zhu L, Hempel A, Lin A, Rickard JA, Hall C, Gangatirkar P, Yip RK, Cawthorne W, Jacobsen AV, Horne CR, Martin KR, Ioannidis LJ, Hansen DS, Day J, Wicks IP, Law C, Ritchie ME, Bowden R, Hildebrand JM, O’Reilly LA, Silke J, Giulino-Roth L, Tsui E, Rogers KL, Hawkins ED, Christensen B, Murphy JM, Samson AL. An immunohistochemical atlas of necroptotic pathway expression. EMBO Molecular Medicine. 2024;16(7):10.1038/s44321-024-00074-6
Meier P, Legrand AJ, Adam D, Silke J. Immunogenic cell death in cancer: targeting necroptosis to induce antitumour immunity. Nature Reviews Cancer. 2024;24(5):10.1038/s41568-024-00674-x
Tran HT, Kratina T, Coutansais A, Michalek D, Hogan BM, Lawlor KE, Vince JE, Silke J, Lalaoui N. RIPK3 cleavage is dispensable for necroptosis inhibition but restricts NLRP3 inflammasome activation. Cell Death & Differentiation. 2024;31(5):10.1038/s41418-024-01281-x
Oda H, Manthiram K, Chavan PP, Rieser E, Veli Ö, Kaya Ö, Rauch C, Nakabo S, Kuehn HS, Swart M, Wang Y, Çelik NI, Molitor A, Ziaee V, Movahedi N, Shahrooei M, Parvaneh N, Alipour-olyei N, Carapito R, Xu Q, Preite S, Beck DB, Chae JJ, Nehrebecky M, Ombrello AK, Hoffmann P, Romeo T, Deuitch NT, Matthíasardóttir B, Mullikin J, Komarow H, Stoddard J, Niemela J, Dobbs K, Sweeney CL, Anderton H, Lawlor KE, Yoshitomi H, Yang D, Boehm M, Davis J, Mudd P, Randazzo D, Tsai WL, Gadina M, Kaplan MJ, Toguchida J, Mayer CT, Rosenzweig SD, Notarangelo LD, Iwai K, Silke J, Schwartzberg PL, Boisson B, Casanova J-L, Bahram S, Rao AP, Peltzer N, Walczak H, Lalaoui N, Aksentijevich I, Kastner DL. Biallelic human SHARPIN loss of function induces autoinflammation and immunodeficiency. Nature Immunology. 2024;25(5):10.1038/s41590-024-01817-w