Nordmann T, Anderton H, Hasegawa A, Schweizer L, Zhang P, Stadler P, Sinha A, Andreas M, Florian R, Maximilian Z, Satoh TK, Saito Y, Gong T, Thielert M, Kimura H, Nguyen H, Levesque M, Murray P, Ingen-Housz-Oro S, Mund A, Abe R, Silke J, Ji C, French LE, Mann M. 720 Cell-type resolved spatial proteomics uncovers a novel actionable therapeutic target in toxic epidermal necrolysis. Journal of Investigative Dermatology. 2024;144(8):10.1016/j.jid.2024.06.736
Chiou S, Al-Ani AH, Pan Y, Patel KM, Kong IY, Whitehead LW, Light A, Young SN, Barrios M, Sargeant C, Rajasekhar P, Zhu L, Hempel A, Lin A, Rickard JA, Hall C, Gangatirkar P, Yip RK, Cawthorne W, Jacobsen AV, Horne CR, Martin KR, Ioannidis LJ, Hansen DS, Day J, Wicks IP, Law C, Ritchie ME, Bowden R, Hildebrand JM, O’Reilly LA, Silke J, Giulino-Roth L, Tsui E, Rogers KL, Hawkins ED, Christensen B, Murphy JM, Samson AL. An immunohistochemical atlas of necroptotic pathway expression. EMBO Molecular Medicine. 2024;16(7):10.1038/s44321-024-00074-6
Meier P, Legrand AJ, Adam D, Silke J. Immunogenic cell death in cancer: targeting necroptosis to induce antitumour immunity. Nature Reviews Cancer. 2024;24(5):10.1038/s41568-024-00674-x
Tran HT, Kratina T, Coutansais A, Michalek D, Hogan BM, Lawlor KE, Vince JE, Silke J, Lalaoui N. RIPK3 cleavage is dispensable for necroptosis inhibition but restricts NLRP3 inflammasome activation. Cell Death & Differentiation. 2024;31(5):10.1038/s41418-024-01281-x
Oda H, Manthiram K, Chavan PP, Rieser E, Veli Ö, Kaya Ö, Rauch C, Nakabo S, Kuehn HS, Swart M, Wang Y, Çelik NI, Molitor A, Ziaee V, Movahedi N, Shahrooei M, Parvaneh N, Alipour-olyei N, Carapito R, Xu Q, Preite S, Beck DB, Chae JJ, Nehrebecky M, Ombrello AK, Hoffmann P, Romeo T, Deuitch NT, Matthíasardóttir B, Mullikin J, Komarow H, Stoddard J, Niemela J, Dobbs K, Sweeney CL, Anderton H, Lawlor KE, Yoshitomi H, Yang D, Boehm M, Davis J, Mudd P, Randazzo D, Tsai WL, Gadina M, Kaplan MJ, Toguchida J, Mayer CT, Rosenzweig SD, Notarangelo LD, Iwai K, Silke J, Schwartzberg PL, Boisson B, Casanova J-L, Bahram S, Rao AP, Peltzer N, Walczak H, Lalaoui N, Aksentijevich I, Kastner DL. Biallelic human SHARPIN loss of function induces autoinflammation and immunodeficiency. Nature Immunology. 2024;25(5):10.1038/s41590-024-01817-w
Gupta N, Silke J. Blocking cell death limits lung damage and inflammation from influenza. Nature. 2024;628(8009):10.1038/d41586-024-00910-2
Wang P, Silke J. RIPK1 and necroptosis role in premature ageing. Nature Cell Biology. 2024;26(4):10.1038/s41556-024-01390-2
Simpson DS, Anderton H, Yousef J, Vaibhav V, Cobbold SA, Bandala-Sanchez E, Kueh AJ, Dagley LF, Herold MJ, Silke J, Vince JE, Feltham R. Mind bomb 2 limits inflammatory dermatitis in Sharpin mutant mice independently of cell death. PNAS Nexus. 2023;3(1):10.1093/pnasnexus/pgad438
Schorn F, Werthenbach JP, Hoffmann M, Daoud M, Stachelscheid J, Schiffmann LM, Hildebrandt X, Lyu SI, Peltzer N, Quaas A, Vucic D, Silke J, Pasparakis M, Kashkar H. cIAPs control RIPK1 kinase activity‐dependent and ‐independent cell death and tissue inflammation. The EMBO Journal. 2023;42(22):10.15252/embj.2023113614
Chu S, Carolan A, Giatrakis C, Nguyen T, Alexiadis M, Yu T, Silke J, Fuller PJ. OR05-06 Histone Deacetylase Inhibitor, Panobinostat, In Combination With A Smac-mimetic For The Treatment Of Ovarian Granulosa Cell Tumours. Journal of the Endocrine Society. 2023;7(Supplement_1):10.1210/jendso/bvad114.2192
