-

Animals in research

WEHI is committed to ensuring that all animals involved in our life-saving medical research are treated ethically and humanely. We take a best practice approach to animal welfare.

The use of animals for medical research plays a vital role in increasing our understanding of complex biological processes and diseases, and in the development of new treatments and diagnostics, all with the ultimate goal of helping people live healthier, for longer.

Research on animal models has been critical to WEHI discoveries that have helped millions of people around the world, including:

At WEHI, we only use animals in research when they are absolutely essential, and work hard to replace the use of animal models wherever possible.  In line with this commitment, we use a range of approaches in our research including cell cultures, computer modelling, and organoid technologies. We are also significantly investing in and expanding our human-based research capabilities.

We use animals in WEHI research when we need to find out what happens in the whole living body, which is far more complex than the sum of its parts. It’s very difficult, and in most cases not yet possible, to develop non-animal methods to replace the use of animals.

The animals used in research at WEHI are mice, rats, rabbits and zebrafish. Some research is also conducted using fruit flies and mosquitos. These animals and insects are used for fundamental research across a range of disease areas including cancer, allergy, asthma, autoimmune diseases, immune deficiencies, neurodevelopmental disorders and infectious diseases, such as malaria, HIV, hepatitis virus B and SARS-CoV-2.

WEHI’s highly skilled animal technicians care for the animals, they are monitored closely and managed according to relevant guidelines and procedures, approved by the Animal Ethics Committee.

Animal Ethics Committee

The use of animals at WEHI is overseen by the Animal Ethics Committee.

This independent committee includes representatives from animal welfare organisations, veterinarians, the wider community, researchers and WEHI animal technicians.

The Animal Ethics Committee is a requirement under the laws that regulate the use of animals for scientific research. No research involving animals can proceed at WEHI unless it is approved by the committee.

The use of animals for research is bound by strict regulations, including Victorian laws and the Australian Code for the Care and Use of Animals for Scientific Purposes.

Openness Agreement on Animal Research

WEHI is an inaugural signatory to the Openness Agreement on Animal Research in Australia.

The institute supports the four commitments of the Openness Agreement:

  1. We will be open about our involvement in the use of animals in research or teaching.
  2. We will enhance our communications with the media and the public about our use of animals in research or teaching.
  3. We will be proactive in providing opportunities for the public to find out about research or teaching involving animals.
  4. We will report annually on our efforts to improve openness in our use of animals in research or teaching.

To find out more about the use of animals in research, you may wish to visit the website of Understanding Animal Research Oceania, an Australian not-for-profit organisation that supports greater understanding of how and why animals are used in medical and scientific research.

For more information, contact: ethics@wehi.edu.au

Sign up to our quarterly newsletter Illuminate

Find out about recent discoveries, community supporters and more.

Illuminate Winter 2024
View the current issue