Lab focus: Whole-organism, pathogen, cellular (single-cell and spatial) and high-throughput functional genomics.
‘Genomics’ is the study of the instruction book of life, or genome, of every organism. Genomics encompasses the measurement of all forms of genetic material (RNA and DNA) as it is passed from one individual to another and expressed to give each cell and tissue its unique character. Genomics includes the study of organisms, populations and collections of thousands of individual cells as they develop, function and reproduce, in health and disease.
The Bowden Laboratory is interested in improving how we study genomes and their organisation and expression, focusing particularly on infection, the study of individual cells, and ways to exploit DNA sequencing to develop new treatments for disease.
Our laboratory hosts the WEHI Advanced Genomics facility (https://www.wehi.edu.au/facilities/the-wehi-advanced-genomics-facility/). We support WEHI in accessing all forms of genomics technology, through a comprehensive suite of advanced preparation platforms and sequencing technologies, and a dynamic R&D program that matches WEHI’s areas of scientific focus.