Lab focus: Whole-organism, pathogen, cellular (single-cell and spatial) and high-throughput functional genomics.
‘Genomics’ is the study of the instruction book of life, or genome, of every organism. Genomics encompasses the measurement of all forms of genetic material (RNA and DNA) as it is passed from one individual to another and expressed to give each cell and tissue its unique character. Genomics includes the study of organisms, populations and collections of thousands of individual cells as they develop, function and reproduce, in health and disease.
The Bowden Laboratory is interested in improving how we study genomes and their organisation and expression, focusing particularly on infection, the study of individual cells, and ways to exploit DNA sequencing to develop new treatments for disease.
Our laboratory hosts the WEHI Advanced Genomics facility. We support WEHI in accessing all forms of genomics technology, through a comprehensive suite of advanced preparation platforms and sequencing technologies, and a dynamic R&D program that matches WEHI’s areas of scientific focus.
Our mission is Omics for All.
Our vision is to lead in Australia in genomics innovation and providing access to omics technologies.
We are the leading group providing access to cellular omics technologies in Melbourne. We implement advanced methodologies and create new and updated applications for sequencing and measuring gene expression and genome variation. We are working towards equitable access to advanced technologies.
The Cellular Genomics (Projects) team provides single-cell omics, spatial and high-throughput transcriptomics solutions, spanning project design, the application of cutting-edge approaches, and data analysis. Our involvement in your project may range from consultations and transactional services to collaborative projects inside and outside WEHI.
The WEHI Genomics Hub was established in 2013 to operate sequencing platforms for the institute, in conjunction with a genomics ‘hotel’, conceived for scientists to access the specialist facilities and expertise needed to prepare their own samples for analysis.
Since its inception, more than 500 WEHI scientists and external collaborators have benefited from the facility, and the complement of sequencing platforms has grown to include Illumina, PacBio, Oxford Nanopore, and MGI instruments.
We are building on our expertise and track record in genomics innovation to expand the reach of our research and development (R&D) team from cellular genomics into other areas of scientific priority for WEHI, including population health and cohort studies, precision medicine and diagnostics, therapeutic discovery and further advanced genomics and sequencing technologies.
Building on our strengths in applying genomics methods to the efficient, high-throughput, unbiased detection and analysis of pathogen genomes, we are setting up projects in diagnostic methods and studies of host-pathogen interactions, with applications in respiratory infection, population health and infectious disease immunology, and infection in immunosuppressed patients.
We are recruiting a post-doctoral research officer, who will work closely with the lab’s Genomics R&D team.
Our laboratory is highly collaborative. As one of WEHI’s key core technology platforms, we work alongside the other scientists in the Advanced Technology and Biology division and with researchers from across WEHI. We have international backgrounds and experience at some of the world’s leading scientific and medical research institutes.
We aim to establish a centre of excellence for broad-based genomics in Melbourne. We are expanding our team to provide access to a full range of advanced sequencing platforms, collaborative execution of genomics projects and cutting-edge technologies.
If you are interested in working in any aspect of genomics, from sequencing to analysis, advanced genomics or innovation, please get in touch by email and find advertised positions on the WEHI jobs page.