Each cell in the body contains the same genetic code, and the interpretation of that code gives rise to a diverse array of cell types and structures. Gene expression is the fundamental first step in the interpretation of the cell’s genetic code. Precise programs of gene expression and regulation are essential for normal development and are disrupted in disease.
New technologies enables us to measure gene expression and other genetic information in individual cells, leading to exciting discoveries. The focus of our research is developing novel bioinformatics methods to better analyse the massive datasets arising from single cell and related technologies