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WEHI has research projects in cancer, immunology and infectious diseases, feeding into our robust discovery and development pipeline. We are committed to the translation of our discoveries into improvements in disease diagnosis, prevention and treatment.
Project name | Theme | Stage | Modality |
---|---|---|---|
Hit-to-Lead | Cell therapy | ||
Hit Discovery | Cell therapy | ||
Hit Discovery | Biologics | ||
Target Validation | Biologics | ||
Lead Optimisation | Small molecule | ||
Lead optimisation | Small molecule | ||
Hit-to-Lead | Diagnostic | ||
Hit Discovery | Vaccine | ||
Hit-to-Lead | Small molecule | ||
Hit Discovery | Small molecule | ||
Hit Discovery | Small molecule | ||
Hit Discovery | Biologics | ||
Currently used by 3 external animal research institutions | Software |
A DC subset with superior antigen-presenting capability, engineered with a proprietary CAR design for immunotherapy.
Platform technology to make CAR-T cell therapy less toxic while improving efficacy​.
A new therapy for global prevention of hemolytic disease of the newborn
Method to induce stem-like memory T cells for long-lived response in vaccine design
Oral therapeutic targeting diverse coronavirus PLpros; potential to minimise progression to severe disease and post-acute sequelae of COVID-19 (PASC / Long COVID).
Oral therapeutic targeting coronavirus Mpro; potential to minimise progression to severe disease and post-acute sequelae of COVID-19 (PASC / Long COVID).
A high-throughput laboratory-based diagnostic for detecting hidden or cryptic liver stage Plasmodium vivax infections.
A genetically-defined, attenuated parasite strain to protect sheep and other mammals from Toxoplasma infection
Using an epigenetic approach to turn on genes, the absence of which causes Prader Willi Syndrome, a devistating neurodevelopment disorder
Disrupting cell death pathways to prevent a number of diseases including Parkinson’s.
Platform developing TPDs against cancer, including novel E3 ligase warheads.
Develop specific and potent inhibitors of IL-11 signaling as novel therapies for cancer and fibro-inflammatory disease.
A comprehensive software as a service system for managing research animals and ethics.