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Partnering opportunities

Bridging the gap between laboratory discoveries and commercial innovation

WEHI has research projects in cancer, immunology and infectious diseases, feeding into our robust discovery and development pipeline. We are committed to the translation of our discoveries into improvements in disease diagnosis, prevention and treatment.

Colourful scientific image from Art of Science 2023

Active Projects

Cancer

Next generation DC therapy

A DC subset with superior antigen-presenting capability, engineered with a proprietary CAR design for immunotherapy.

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Stage
Hit-to-Lead
Theme
Cancer
Project contact
Ewa Michalak
michalak.e@wehi.edu.au

Safer CAR-T cells

Platform technology to make CAR-T cell therapy less toxic while improving efficacy​.

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Stage
Hit Discovery
Theme
Cancer
Project contact
Ewa Michalak
michalak.e@wehi.edu.au

Immunology and inflammation

A therapy for haemolytic disease

A new therapy for global prevention of hemolytic disease of the newborn

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Stage
Hit Discovery
Theme
Immunology and inflammation
Project contact
Onisha Patel
patel.o@wehi.edu.au

Enzyme X

A new therapy for Cardiometabolic diseases

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Stage
Hit Discovery
Theme
Immunology and inflammation
Project contact
Onisha Patel
patel.o@wehi.edu.au

Improving T cell memory

Method to induce stem-like memory T cells for long-lived response in vaccine design

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Stage
Target Validation
Theme
Immunology and inflammation
Project contact
Onisha Patel
patel.o@wehi.edu.au

Global health and infection

VirPRO – targeting Mpro

Oral therapeutic targeting diverse coronavirus PLpros; potential to minimise progression to severe disease and post-acute sequelae of COVID-19 (PASC / Long COVID).

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Stage
Lead Optimisation
Theme
Global health and infection
Project contact
Victoria Jameson
jameson.v@wehi.edu.au

VirDUB – targeting PLPro

Oral therapeutic targeting coronavirus Mpro; potential to minimise progression to severe disease and post-acute sequelae of COVID-19 (PASC / Long COVID).

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Stage
Lead optimisation
Theme
Global health and infection
Project contact
Victoria Jameson
jameson.v@wehi.edu.au

P. vivax diagnostic

A high-throughput laboratory-based diagnostic for detecting hidden or cryptic liver stage Plasmodium vivax infections.

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Stage
Hit-to-Lead
Theme
Global health and infection
Project contact
Victoria Jameson
jameson.v@wehi.edu.au

Toxoplasma Vaccine

A genetically-defined, attenuated parasite strain to protect sheep and other mammals from Toxoplasma infection

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Stage
Hit Discovery
Theme
Global health and infection
Project contact
Victoria Jameson
jameson.v@wehi.edu.au

Neurological disorders

Precision epigenetics

Using an epigenetic approach to turn on genes, the absence of which causes Prader Willi Syndrome, a devistating neurodevelopment disorder

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Stage
Hit-to-Lead
Theme
Neurological disorders
Project contact
Leo Lui
lui.l@wehi.edu.au

Inhibitors of apoptosis

Disrupting cell death pathways to prevent a number of diseases including Parkinson’s.

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Stage
Hit Discovery
Theme
Neurological disorders
Project contact
Leo Lui
lui.l@wehi.edu.au

Platform technologies

E3 ligase warheads/ACTT

Platform developing TPDs against cancer, including novel E3 ligase warheads.

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Stage
Hit Discovery
Theme
Platform technologies
Project contact
Leo Lui
lui.l@wehi.edu.au

IL-11 signaling

Develop specific and potent inhibitors of IL-11 signaling as novel therapies for cancer and fibro-inflammatory disease.

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Stage
Hit Discovery
Theme
Platform technologies
Project contact
Leo Lui
lui.l@wehi.edu.au

Digital health

Animal management system

A comprehensive software as a service system for managing research animals and ethics.

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Stage
Currently used by 3 external animal research institutions
Theme
Digital health
Project contact
Michelle Kleynhans
kleynhans.m@wehi.edu.au
Contact us

To discuss partnering opportunities and collaborations please contact our team.

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Illuminate Autumn 2024
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