We also work with institutional partners and selected collaborators around the Melbourne Biomedical Precinct to lower the financial and logistical barriers to entry into advanced genomics.
We operate at several levels:
For general queries about our activities and interests, please e-mail Dr Rory Bowden.
The WEHI Advanced Genomics Platforms Team operates a suite of sequencing and other genomics instruments, including Illumina MiSeq and NextSeq 500, Oxford Nanopore PromethION, MGI and PacBio Sequel, alongside 10x Genomics Chromium and MissionBio Tapestri.
We provide sequencing as a service to internal users, for Cellular Genomics projects, and on a limited basis to external researchers.
Please contact Dr Stephen Wilcox for more information.
The Cellular Genomics Projects Team, formerly SCORE, provides single-cell and spatial omics, high-throughput transcriptomics and other advanced genomics capacity to WEHI researchers, institutional partners and selected collaborators around the Melbourne Biomedical Precinct.
We operate an integrated platform where biologists, technologists and computational biologists collaborate to apply the latest approaches to basic and clinical research questions, often with the assistance of our R&D team. By bringing a full suite of technologies together in one place we lower the financial and logistical barriers to entry into advanced genomics.
Our advanced genomics technologies and expertise are available to medical and scientific researchers on a cost-recovery basis, under terms that depend on your institution’s affiliation with WEHI and our available capacity.
Please contact Dr Daniela Zalcenstein to discuss how we can work with you.
We offer multiple options for the transcriptomic analysis of collections of single cells. We help researchers identify the protocol and experimental design best suited to their needs and resources, and undertake projects in a highly collaborative environment. A typical project will involve five stages:
Members of the WEHI Genomics Lab, which hosts the WEHI Advanced Genomics Facility, have a substantial track record of adapting and implementing genomics methodologies and sequencing workflows, both for cellular genomics and in other areas such as pathogen genomics. The R&D Team, alongside the Projects and Platforms Teams, is responsible for the evaluation and introduction of new genomics instrumentation.
Current areas of R&D priority include:
The Genomics R&D Team supports a proportion of Cellular Genomics projects that require methods development or validation on a collaborative basis.
We also undertake collaborative proof-of-concept studies in preparation for introducing new technologies and applications, and to support applications for scientific project funding.
Please contact Dr Rory Bowden to discuss collaborative opportunities.
Cell behaviour is controlled by the cells’ genetic material, made up of DNA. Genomics is the study of the entire DNA content of a cell or organism (its genome).
Our researchers are using genomics to better understand how diseases develop, and to discover new ways to diagnose and treat disease.