Myeloproliferative disorders

Myeloproliferative disorders are serious conditions in which excessive numbers of blood cells are produced. This can interfere with the normal functions of blood.


Myeloproliferative disorders are caused by over-active signalling in blood-producing cells. Our research is focused on understanding this process to develop new treatments for people with these diseases.

Our research into myeloproliferative disorders

Our researchers aim to improve how myeloproliferative disorders are treated by:

  • Revealing how normal blood cell production is controlled, and the defects that lead to myeloproliferative disorders.
  • Understanding the signalling proteins that contribute to myeloproliferative disorders, aiding the development of new treatments.
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