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- Domain-specific BET bromodomain inhibitors for cancer
- Targeting BFL-1 for the treatment of cancer
- Jointly targeting IGF-1R and IR in cancer
- Soluble CD52 as a therapeutic for inflammatory disease
- TBK inhibitors to treat rheumatoid arthritis
- A novel therapeutic to treat malaria
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- Associate Professor Aaron Jex
- Associate Professor Alyssa Barry
- Associate Professor Anne Voss
- Associate Professor Chris Tonkin
- Associate Professor Clare Scott
- Associate Professor Joan Heath
- Associate Professor Marnie Blewitt
- Associate Professor Mike Lawrence
- Associate Professor Oliver Sieber
- Associate Professor Peter Gibbs
- Associate Professor Sandra Nicholson
- Associate Professor Seth Masters
- Associate Professor Tim Thomas
- Associate Professor Tony Papenfuss
- Associate Professor Wai-Hong Tham
- Catherine Parker
- Dr Andrew Webb
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- Dr Grant Dewson
- Dr Gwo Yaw Ho
- Dr Hélène Jousset Sabroux
- Dr Ian Majewski
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- Dr Leigh Coultas
- Dr Marco Herold
- Dr Marie-Liesse Asselin-Labat
- Dr Mary Ann Anderson
- Dr Maryam Rashidi
- Dr Matthew Call
- Dr Matthew Ritchie
- Dr Melissa Call
- Dr Melissa Davis
- Dr Michael Low
- Dr Misty Jenkins
- Dr Peter Czabotar
- Dr Philippe Bouillet
- Dr Priscilla Auyeung
- Dr Rhys Allan
- Dr Ruth Kluck
- Dr Samar Ojaimi
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- Dr Shalin Naik
- Dr Simon Chatfield
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- Dr Tracy Putoczki
- Dr Wei Shi
- Guillaume Lessene
- Helene Martin
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- Keely Bumsted-O'Brien
- Mr Ian Coulson
- Mr Simon Monard
- Mr Stan Balbata
- Mr Steve Droste
- Ms Carolyn MacDonald
- Ms Lee Byrne
- Ms Samantha Ludolf
- Ms Susanne Williamson
- Ms Wendy Hertan
- Nicholas Huntington
- Professor Alan Cowman
- Professor Andreas Strasser
- Professor Andrew Lew
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- Professor David Huang
- Professor David Vaux
- Professor Doug Hilton
- Professor Gabrielle Belz
- Professor Geoff Lindeman
- Professor Gordon Smyth
- Professor Ian Wicks
- Professor Ivo Mueller
- Professor Jane Visvader
- Professor Jerry Adams
- Professor John Silke
- Professor Ken Shortman
- Professor Leonard C Harrison
- Professor Li Wu
- Professor Lynn Corcoran
- Professor Marc Pellegrini
- Professor Melanie Bahlo
- Professor Nicos Nicola
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- Professor Suzanne Cory
- Professor Terry Speed
- Professor Tony Burgess
- Professor Warren Alexander
- Education
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- Analysis and reporting of whole genome sequencing data from malaria parasites
- Analysis of long read data from the minION, with application to malaria
- Analysis of short tandem repeat markers from whole genome sequencing
- Antibody longevity following Plasmodium vivax infections
- Antigenic diversity of malaria parasites: towards more effective malaria vaccines
- Biogenesis of eosinophil granules
- Biological sequence analysis and genomic variant discovery
- Biology of the unique intra-mitochondrial bacterium Midichloria mitochondrii
- Characterising regulatory T cells in coeliac disease
- Chemical probing to identify effectors of necroptotic cell death
- Computational systems biology of Wnt/cell adhesion signalling in colon cancer
- Controlling apoptotic cell death in cancer
- Deciphering mechanisms of thrombocytopenia (low platelet count) in blood cancers
- Defining molecular signatures of drug resistance and sensitivity
- Designing immunotherapy for brain cancer
- Developing non-invasive methods to monitor kidney transplant rejection
- Discovery and analysis of autoimmune regulators
- Discovery of novel drug combinations for the treatment of bowel cancer
- Drug targets and compounds that block growth of malaria parasites
- Dying to survive: mechanistic insights into human bowel cancer development
- Dynamic discovery of innate immunity through imaging and genomics
- Dysregulation of TNF expression in inflammatory diseases
- Effects of nutrition on immunity and infection in Asia and Africa
- Elucidation of long range methylation structure using nanopore sequencing
- Eosinophil activation
- Eosinophil death
- Eosinophil heterogeneity
- Eosinophil maturation
- Epigenetic regulation of systemic iron homeostasis
- Epigenetic regulation of the immune system
- Explosive cell death and human disease
- Export of malaria virulence proteins during liver infection
- Function of proteins involved in invasion of erythrocytes by malaria parasites
- Functional genomics to improve therapeutic options for rare cancers
- Giardia duodenalis phosphoproteome and protein kinase network
- Harnessing the immune system to target small cell lung cancer
- Home renovations: understanding how Toxoplasma redecorates its host cell
- How do malaria parasites traverse human cells and invade hepatocytes?
- How does the malaria parasite prevent the host liver cell from dying?
- Human monoclonal antibodies against malaria infection
- IL5 signalling in asthma
- Identification of genes critical for the control of chronic infections
- Identification of malaria parasite entry receptors
- Identifying new cell death and inflammatory pathways
- Identifying proteome signatures of high grade glioma for precision medicine
- Insight into the cytotoxic T cell immune synapse
- Investigating apoptosis control in tumour blood vessels
- Investigating brain abnormalities with single cell ‘omics
- Investigating mechanisms of cell death and survival using zebrafish
- Investigating the mechanics of platelet formation
- Investigating the molecular regulation of neovascular eye disease
- Let me in! How Toxoplasma invades human cells
- Long-read sequencing for transcriptome and epigenome analysis
- Machine learning analysis of mutagenesis datasets
- Macro-evolution in cancer
- Mapping human gene mutations affecting anti-malarial drug efficacy
- Mechanism and modulation of K+ channels and membrane transporters
- Mechanisms of disease relapse in acute lymphoblastic leukaemia
- Microbiome analysis using long read nanopore sequencing
- Molecular mechanism underpinning dendritic cell ontogeny and functions
- Molecular mechanisms of innate immune signalling
- Next-generation mucolytics to treat lung diseases
- No sex please, we’re inhibited: searching for drugs to prevent malaria transmission
- Novel biomarkers and mechanisms of antimalarial drug resistance
- Novel real-time, quantitative imaging approaches for studying malaria
- Novel regulators of JAK-STAT signalling in development and disease
- Novel tool for malaria surveillance and intervention
- Optimising serological markers of recent exposure to Plasmodium vivax
- Quantitation of human T cell responses in primary immunodeficiency
- Reconciling intracellular imaging and metastatic behaviour in cancer cells
- Reconstructing the immune response: from molecules to cells to systems
- Role of protein glycosylation in malaria virulence
- Statistical bioinformatic analyses of RNA-seq and ChIP-seq data
- Strategies mammalian cells use to survive without growth factors
- Structural and biochemical studies on Notch signal transduction
- Structural and functional analysis of malaria invasion
- Structural biology and binding studies of BCL-2 family proteins
- Structural studies of invasion processes during malaria infection
- Structural studies of the Plasmodium and Toxoplasma tight-junction complex
- Target identification of potent antimalarial agents
- The role of glycosylation in malaria vaccine design
- Towards a molecular description of plasma cell diversity
- Tracking the spread of malaria in the Asia Pacific region
- Transmembrane control of type I cytokine receptor activation
- Uncovering the roles of long non-coding RNAs in human bowel cancer
- Understanding resistance to apoptotic cell death
- Understanding the common through study of the rare
- Understanding the development of humoral immunity to malaria
- Unravelling cellular circuitry with single cell RNA-seq and CRISPR
- Unravelling the molecular architecture of killer T cells in disease
- Why is interleukin-11 elevated in acute myeloid leukaemia?
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- Helping uncover the causes of rheumatoid arthritis
- An inspiring story of philanthropy
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- Renewed support for HIV eradication project
- Searching for solutions to muscular dystrophy
- Supporting research into better treatments for colon cancer
- Taking a single cell focus with the DROP-seq
- Working towards personalised treatments for cancer
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Welcome to the Walter and Eliza Hall Institute of Medical Research
Super Content:
Celebrating 100 years of discoveries for humanity
For more than 100 years, the institute’s discoveries have advanced scientific thinking, improved clinical practice and resulted in new and more effective treatments for patients.
As we look to the future and what it will hold for medical research, we are developing strategies to ensure we continue to make discoveries that improve lives and benefit humanity.
Discover our research
News
The Walter and Eliza Hall Institute supports marriage equality
The Institute values diversity and inclusion and the many freedoms that are integral to a free, fair and equitable society.
18 September 2017
Carbohydrates may be the key to a better malaria vaccine
Melbourne researchers have shown for the first time that carbohydrates on the surface of malaria parasites play a critical role in malaria’s ability to infect mosquito and human hosts.
15 September 2017
'Missing link' explains how viruses trigger immunity
A discovery by Melbourne researchers has solved a longstanding mystery of how viruses trigger protective immunity within our body.
12 September 2017
'Mix and match' assembly instructions guide immune cell attacks
Institute researchers have discovered how immune cells use a unique set of assembly instructions to ‘mix and match’ how they respond to, and kill, tumour and diseased cells.
5 September 2017
Events
Thu, 28/09/2017 - 11:00am to
Thu, 28/09/2017 - 12:00pm
CRISPR-Cas9 genome editing, from mechanism to therapy
Wed, 04/10/2017 - 1:00pm to
Wed, 04/10/2017 - 2:00pm
The impact of burden of disease on Indigenous Australians
Mon, 09/10/2017 - 3:00pm to
Mon, 09/10/2017 - 4:00pm
Aspartyl protease 5 is essential for export of Toxoplasma proteins into the host cell
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