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About

I am the Proteomics Facility manager at The Walter and Eliza Hall Institute (WEHI). I have over 13 years’ experience in the application of novel mass spectrometry and proteomics technologies to address key research questions in the fields of infectious & inflammatory diseases and cancer. In 2009, I received a postgraduate scholarship from Multiple Sclerosis Research Australia to pursue my PhD with Prof. Tony Purcell (Monash). In 2010, I was awarded funding from multiple sources to continue my PhD research at the University of Toronto, Canada (with Prof. Andrew Emili). Here, I received world-class training in the use of mass spectrometry instruments and published collaborative research in top-tier proteomics journals. During my postdoctoral training at WEHI with Dr. Sandra Nicholson (2013-2015) and then A/Prof. Andrew Webb (2015-2020), I applied my comprehensive mass spectrometry training to address novel research questions, facilitating a range of productive research collaborations resulting in 8 first/co-first author publications in leading journals (including Nature Immunology). I am an active board member of the Australasian Proteomics Society (APS) executive committee and the Human Proteome Organisation (HUPO) Award committee.

Publications

Selected publications from Dr Laura Dagley

Cai T, Emery-Corbin SJ, McCafferty C, Van Den Helm S, Letunica N, Barton R, Attard C, Horton S, Bottrell S, Schultz B, MacLaren G, Chiletti R, Best D, Johansen A, Newall F, Butt W, d’Udekem Y, Dagley LF, Yousef JM, Monagle P, Ignjatovic V. Characterization of Protein Binding on an Extracorporeal Membrane Oxygenation (ECMO) Circuit Following the Priming Procedure.ASAIO Journal. 2024;:10.1097/mat.0000000000002273

Leinenga G, To XV, Bodea L-G, Yousef J, Richter-Stretton G, Palliyaguru T, Chicoteau A, Dagley L, Nasrallah F, Götz J. Correction: Scanning ultrasound-mediated memory and functional improvements do not require amyloid-β reduction. Molecular Psychiatry. 2024;:10.1038/s41380-024-02616-3

Fan F, Babl FE, Swaney EEK, Hearps SJC, Takagi M, Emery-Corbin SJ, Dagley LF, Yousef J, Parkin GM, Rausa VC, Anderson N, Fabiano F, Dunne K, Seal M, Davis GA, Attard C, Anderson V, Ignjatovic V. Capillary blood protein markers of posttraumatic headache in children after concussion.Journal of Neurosurgery Pediatrics. 2024;33(6):10.3171/2024.2.peds23551

Emery‐Corbin SJ, Yousef JM, Adhikari S, Sumardy F, Nhu D, van Delft MF, Lessene G, Dziekan J, Webb AI, Dagley LF. Improved drug target deconvolution with PISA‐DIA using an extended, overlapping temperature gradient. Proteomics. 2024;:10.1002/pmic.202300644

Leinenga G, To XV, Bodea L-G, Yousef J, Richter-Stretton G, Palliyaguru T, Chicoteau A, Dagley L, Nasrallah F, Götz J. Scanning ultrasound-mediated memory and functional improvements do not require amyloid-β reduction. Molecular Psychiatry. 2024;:10.1038/s41380-024-02509-5

Dagley LF, Yousef J, Preaudet A, Loving A, Webb AI, Ernst M, Putoczki TL. Identification of Serum Biomarkers to Monitor Therapeutic Response in Intestinal-Type Gastric Cancer. International Journal of Molecular Sciences. 2024;25(6):10.3390/ijms25063129

Dawar S, Benitez MC, Lim Y, Dite TA, Yousef JM, Thio N, Garciaz S, Jackson TD, Milne JV, Dagley LF, Phillips WA, Kumar S, Clemons NJ. Caspase-2 protects against ferroptotic cell death. Cell Death & Disease. 2024;15(3):10.1038/s41419-024-06560-6

Delconte RB, Kolesnik TB, Dagley LF, Rautela J, Shi W, Putz EM, Stannard K, Zhang J-G, Teh C, Firth M, Ushiki T, Andoniou CE, Degli-Esposti MA, Sharp PP, Sanvitale CE, Infusini G, Liau NPD, Linossi EM, Burns CJ, Carotta S, Gray DHD, Seillet C, Hutchinson DS, Belz GT, Webb AI, Alexander WS, Li SS, Bullock AN, Babon JJ, Smyth MJ, Nicholson SE, Huntington ND. Author Correction: CIS is a potent checkpoint in NK cell–mediated tumor immunity. Nature Immunology. 2024;25(2):10.1038/s41590-023-01714-8

Fietz D, Sgaier R, O’Donnell L, Stanton PG, Dagley LF, Webb AI, Schuppe H-C, Diemer T, Pilatz A. Proteomic biomarkers in seminal plasma as predictors of reproductive potential in azoospermic men. Frontiers in Endocrinology. 2024;15:10.3389/fendo.2024.1327800

Low RRJ, Fung KY, Dagley LF, Yousef J, Emery-Corbin SJ, Putoczki TL. Unbiased Quantitative Proteomics of Organoid Models of Pancreatic Cancer. Methods in Molecular Biology. 2024;2823:10.1007/978-1-0716-3922-1_6

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