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About

I am the Proteomics Facility manager at The Walter and Eliza Hall Institute (WEHI). I have over 13 years’ experience in the application of novel mass spectrometry and proteomics technologies to address key research questions in the fields of infectious & inflammatory diseases and cancer. In 2009, I received a postgraduate scholarship from Multiple Sclerosis Research Australia to pursue my PhD with Prof. Tony Purcell (Monash). In 2010, I was awarded funding from multiple sources to continue my PhD research at the University of Toronto, Canada (with Prof. Andrew Emili). Here, I received world-class training in the use of mass spectrometry instruments and published collaborative research in top-tier proteomics journals. During my postdoctoral training at WEHI with Dr. Sandra Nicholson (2013-2015) and then A/Prof. Andrew Webb (2015-2020), I applied my comprehensive mass spectrometry training to address novel research questions, facilitating a range of productive research collaborations resulting in 8 first/co-first author publications in leading journals (including Nature Immunology). I am an active board member of the Australasian Proteomics Society (APS) executive committee and the Human Proteome Organisation (HUPO) Award committee.

Publications

Selected publications from Dr Laura Dagley

Geyer PE, Hornburg D, Pernemalm M, Hauck SM, Palaniappan KK, Albrecht V, Dagley LF, Moritz RL, Yu X, Edfors F, Vandenbrouck Y, Mueller-Reif JB, Sun Z, Brun V, Ahadi S, Omenn GS, Deutsch EW, Schwenk JM. The Circulating ProteomeTechnological Developments, Current Challenges, and Future Trends. Journal of Proteome Research. 2024;23(12):10.1021/acs.jproteome.4c00586

Leinenga G, To XV, Bodea L-G, Yousef J, Richter-Stretton G, Palliyaguru T, Chicoteau A, Dagley L, Nasrallah F, Götz J. Correction: Scanning ultrasound-mediated memory and functional improvements do not require amyloid-β reduction. Molecular Psychiatry. 2024;29(12):10.1038/s41380-024-02616-3

Kauppi M, Hyland CD, Viney EM, White CA, de Graaf CA, Welch AE, Yousef J, Dagley LF, Emery-Corbin SJ, Di Rago L, Kueh AJ, Herold MJ, Hilton DJ, Babon JJ, Nicola NA, Behrens K, Alexander WS. Cullin-5 controls the number of megakaryocyte-committed stem cells to prevent thrombocytosis in mice. Blood. 2024;:10.1182/blood.2024025406

Cai T, Emery-Corbin SJ, McCafferty C, Van Den Helm S, Letunica N, Attard C, Barton R, Horton S, Bottrell S, Schultz B, MacLaren G, Chiletti R, Best D, Johansen A, Newall F, Butt W, d’Udekem Y, Dagley LF, Yousef JM, Monagle P, Ignjatovic V. Comprehensive Characterization of Surface-Bound Proteins and Measurement of Fibrin Fiber Thickness on Extracorporeal Membrane Oxygenation Circuits Collected From Patients*. Pediatric Critical Care Medicine. 2024;25(11):10.1097/pcc.0000000000003591

Leinenga G, To XV, Bodea L-G, Yousef J, Richter-Stretton G, Palliyaguru T, Chicoteau A, Dagley L, Nasrallah F, Götz J. Scanning ultrasound-mediated memory and functional improvements do not require amyloid-β reduction. Molecular Psychiatry. 2024;29(8):10.1038/s41380-024-02509-5

Emery‐Corbin SJ, Yousef JM, Adhikari S, Sumardy F, Nhu D, van Delft MF, Lessene G, Dziekan J, Webb AI, Dagley LF. Improved drug target deconvolution with PISA‐DIA using an extended, overlapping temperature gradient. Proteomics. 2024;24(16):10.1002/pmic.202300644

Cai T, Emery-Corbin SJ, McCafferty C, Van Den Helm S, Letunica N, Barton R, Attard C, Horton S, Bottrell S, Schultz B, MacLaren G, Chiletti R, Best D, Johansen A, Newall F, Butt W, d’Udekem Y, Dagley LF, Yousef JM, Monagle P, Ignjatovic V. Characterization of Protein Binding on an Extracorporeal Membrane Oxygenation (ECMO) Circuit Following the Priming Procedure.ASAIO Journal. 2024;:10.1097/mat.0000000000002273

Fan F, Babl FE, Swaney EEK, Hearps SJC, Takagi M, Emery-Corbin SJ, Dagley LF, Yousef J, Parkin GM, Rausa VC, Anderson N, Fabiano F, Dunne K, Seal M, Davis GA, Attard C, Anderson V, Ignjatovic V. Capillary blood protein markers of posttraumatic headache in children after concussion.Journal of Neurosurgery Pediatrics. 2024;33(6):10.3171/2024.2.peds23551

Dagley LF, Yousef J, Preaudet A, Loving A, Webb AI, Ernst M, Putoczki TL. Identification of Serum Biomarkers to Monitor Therapeutic Response in Intestinal-Type Gastric Cancer. International Journal of Molecular Sciences. 2024;25(6):10.3390/ijms25063129

Dawar S, Benitez MC, Lim Y, Dite TA, Yousef JM, Thio N, Garciaz S, Jackson TD, Milne JV, Dagley LF, Phillips WA, Kumar S, Clemons NJ. Caspase-2 protects against ferroptotic cell death. Cell Death & Disease. 2024;15(3):10.1038/s41419-024-06560-6

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