Primary immunodeficiency

Our immune system normally prevents infection. In immunodeficiency, one or more components of the immune system are lacking. This puts people at risk of life-threatening infections.


Our research seeks to discover how immunodeficiencies occur, with the goals of improving diagnosis of immunodeficiencies and how they are treated.

Staff taking a blood donation
Above: Dr Charlotte Slade takes blood for the immunodeficient blood donor initiative

Our immunodeficiency research

Our immunology researchers aim to understand how immunodeficiencies occur, and how they can be better treated. Our laboratory and clinical research efforts include:

  • Defining how the immune system normally develops and functions, to understand what goes wrong in immunodeficiencies.
  • Discovering the genetic and immune changes that cause common variable immunodeficiency, the most common inherited (primary) immunodeficiency in Australia and worldwide.
  • Investigating HIV, a major cause of immunodeficiency worldwide.
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Illuminate Winter 2024
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