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Diseases
Technologies
  • Metabolomic analysis
  • Diagnostics
  • Clinical trials
  • Cohort studies
  • Cohort analysis
  • Mathematical modelling
Themes / Divisions

About

John Wentworth is an adult endocrinologist who holds dual appointments at Royal Melbourne Hospital and WEHI. His work aims to improve treatments and prevention strategies for diabetes.

John’s research focuses on screening to detect type 1 diabetes early and the development of immune therapies to preserve beta cell function. He was the first to introduce at-home finger prick screening for type 1 diabetes in Australia and was lead clinical investigator of the BANDIT trial that showed oral immunotherapy with baricitinib preserves beta cell function.

He collaborates widely with national and international colleagues to run clinical trials. John leads the Type1Screen national islet autoantibody screening program, heads the Australasian T1D Immunotherapy Collaborative (ATIC), is principal investigator of several type 1 diabetes clinical trials and co-investigator for the ENDIA birth-cohort study and the National Screening Pilot.

Publications

Selected publications from Dr John Wentworth

Roberts AG, Tully AS, Binkowski SK, Bebbington KR, Penno MAS, Anderson AJ, Craig ME, Colman PG, Huynh T, McGorm KJ, Soldatos G, Vuillermin PJ, Wentworth JM, Davis EA, Couper JJ, Haynes A. Parental experiences of using continuous glucose monitoring in their young children with early-stage type 1 diabetes: a qualitative interview study. Frontiers in Clinical Diabetes and Healthcare. 2024;5:10.3389/fcdhc.2024.1479948

Bell KJ, Brodie S, Couper JJ, Colman P, Davis E, Deed G, Hagopian W, Haynes A, Hendrieckx C, Henry A, Gordon A, Howard K, Huynh T, Kerr B, Mikler K, Nassar N, Norris S, Oram R, Pawlak D, Shand A, Sinnott RO, Wadling B, Wentworth JM, Craig ME, Group TT1DNSPS. Protocol for the Australian Type 1 Diabetes National Screening Pilot: Assessing the feasibility and acceptability of three general population screening models in children. Diabetic Medicine. 2024;41(11):10.1111/dme.15419

Thomson RL, Brown JD, Oakey H, Palmer K, Ashwood P, Penno MAS, McGorm KJ, Battersby R, Colman PG, Craig ME, Davis EA, Huynh T, Harrison LC, Haynes A, Sinnott RO, Vuillermin PJ, Wentworth JM, Soldatos G, Couper JJ. Dietary patterns during pregnancy and maternal and birth outcomes in women with type 1 diabetes: the Environmental Determinants of Islet Autoimmunity (ENDIA) study. Diabetologia. 2024;67(11):10.1007/s00125-024-06259-5

Wu L, Wentworth J, Liddle C, Carlino M, Brown D, Clifton-Bligh RJ, Long G, Sasson S, Tsang V, Menzies A, Gunton JE. 7760 Identifying Conventional and Novel Biomarkers to Predict Checkpoint Inhibitor Associated Autoimmune Diabetes. Journal of the Endocrine Society. 2024;8(Supplement_1):10.1210/jendso/bvae163.803

Haynes A, Tully A, Smith GJ, Penno MAS, Craig ME, Wentworth JM, Huynh T, Colman PG, Soldatos G, Anderson AJ, McGorm KJ, Oakey H, Couper JJ, Davis EA, Barry SC, Craig ME, Colman PG, Couper JJ, Davis EA, Hamilton-Williams E, Harrison LC, Haynes A, Huynh T, Kim KW, Morahan G, Oakey H, Penno MAS, Rawlinson WD, Sinnott RO, Soldatos G, Thomson RL, Tye-Din J, Vuillermin PJ, Wentworth JM, Cameron F, Day A, Lopez P, Anderson AJ, Ashwood P, Brown JD, Hu W, Huynh D, McGorm KJ, Watson K, Beresford S, Bezuidenhout D, Brandrick S, Butterworth C, Catteau J, Griffiths H, Gwiazdzinski A, Hall C, Hulley A, Henneken L, Kludas R, Mateevici Y, Ramoso B, Roberts A, Tully A, Wood R, Binkowski S, Bui M, Gilbert A, Huang D, Karceva A, Mellor B-R, Naselli G, Ngui K, Nguyen T, Patel B, Prajitno V, Stone N, Tran T, Vaega S, Ward E, Xu Y, Yau C, Battersby R, Brittain B, Foster C, Hope C, Leung P, Mallitt K-A, Roth-Schulze A, Sadlon T, Tillett B, Walker G, Wong Y, Zozaya-Valdes E, Cavenett L. Early Dysglycemia Is Detectable Using Continuous Glucose Monitoring in Very Young Children at Risk of Type 1 Diabetes. Diabetes Care. 2024;47(10):10.2337/dc24-0540

Phillip M, Achenbach P, Addala A, Albanese-O’Neill A, Battelino T, Bell KJ, Besser REJ, Bonifacio E, Colhoun HM, Couper JJ, Craig ME, Danne T, de Beaufort C, Dovc K, Driscoll KA, Dutta S, Ebekozien O, Larsson HE, Feiten DJ, Frohnert BI, Gabbay RA, Gallagher MP, Greenbaum CJ, Griffin KJ, Hagopian W, Haller MJ, Hendrieckx C, Hendriks E, Holt RIG, Hughes L, Ismail HM, Jacobsen LM, Johnson SB, Kolb LE, Kordonouri O, Lange K, Lash RW, Lernmark Å, Libman I, Lundgren M, Maahs DM, Marcovecchio ML, Mathieu C, Miller KM, O’Donnell HK, Oron T, Patil SP, Pop-Busui R, Rewers MJ, Rich SS, Schatz DA, Schulman-Rosenbaum R, Simmons KM, Sims EK, Skyler JS, Smith LB, Speake C, Steck AK, Thomas NPB, Tonyushkina KN, Veijola R, Wentworth JM, Wherrett DK, Wood JR, Ziegler A-G, DiMeglio LA. Consensus guidance for monitoring individuals with islet autoantibody-positive pre-stage 3 type 1 diabetes. Diabetologia. 2024;67(9):10.1007/s00125-024-06205-5

Phillip M, Achenbach P, Addala A, Albanese‑O’Neill A, Battelino T, Bell KJ, Besser REJ, Bonifacio E, Colhoun HM, Couper JJ, Craig ME, Danne T, de Beaufort C, Dovc K, Driscoll KA, Dutta S, Ebekozien O, Larsson HE, Feiten DJ, Frohnert BI, Gabbay RA, Gallagher MP, Greenbaum CJ, Griffin KJ, Hagopian W, Haller MJ, Hendrieckx C, Hendriks E, Holt RIG, Hughes L, Ismail HM, Jacobsen LM, Johnson SB, Kolb LE, Kordonouri O, Lange K, Lash RW, Lernmark Å, Libman I, Lundgren M, Maahs DM, Marcovecchio ML, Mathieu C, Miller KM, O’Donnell HK, Oron T, Patil SP, Pop‑Busui R, Rewers MJ, Rich SS, Schatz DA, Schulman‑Rosenbaum R, Simmons KM, Sims EK, Skyler JS, Smith LB, Speake C, Steck AK, Thomas NPB, Tonyushkina KN, Veijola R, Wentworth JM, Wherrett DK, Wood JR, Ziegler A, DiMeglio LA. Correction to: Consensus guidance for monitoring individuals with islet autoantibody‑positive pre‑stage 3 type 1 diabetes. Diabetologia. 2024;67(9):10.1007/s00125-024-06266-6

Gong JY, Wentworth JM. Resolution of symptoms of binge eating disorder associated with semaglutide treatment for obesity and type 1 diabetes. Internal Medicine Journal. 2024;54(9):10.1111/imj.16499

Phillip M, Achenbach P, Addala A, Albanese-O’Neill A, Battelino T, Bell KJ, Besser REJ, Bonifacio E, Colhoun HM, Couper JJ, Craig ME, Danne T, de Beaufort C, Dovc K, Driscoll KA, Dutta S, Ebekozien O, Elding Larsson H, Feiten DJ, Frohnert BI, Gabbay RA, Gallagher MP, Greenbaum CJ, Griffin KJ, Hagopian W, Haller MJ, Hendrieckx C, Hendriks E, Holt RIG, Hughes L, Ismail HM, Jacobsen LM, Johnson SB, Kolb LE, Kordonouri O, Lange K, Lash RW, Lernmark Å, Libman I, Lundgren M, Maahs DM, Marcovecchio ML, Mathieu C, Miller KM, O’Donnell HK, Oron T, Patil SP, Pop-Busui R, Rewers MJ, Rich SS, Schatz DA, Schulman-Rosenbaum R, Simmons KM, Sims EK, Skyler JS, Smith LB, Speake C, Steck AK, Thomas NPB, Tonyushkina KN, Veijola R, Wentworth JM, Wherrett DK, Wood JR, Ziegler A-G, DiMeglio LA. Consensus Guidance for Monitoring Individuals With Islet Autoantibody-Positive Pre-Stage 3 Type 1 Diabetes.Diabetes Care. 2024;47(8):10.2337/dci24-0042

Thomson RL, Oakey H, Haynes A, Craig ME, Harrison LC, Wentworth JM, Anderson A, Ashwood P, Barry S, Brittain B, Brown JD, Colman PG, Davis EA, Hamilton-Williams E, Huynh D, Huynh T, Kim K-W, McGorm KJ, Morahan G, Rawlinson W, Sinnott RO, Soldatos G, Tye-Din JA, Vuillermin PJ, Penno MAS, Couper JJ. Environmental Determinants of Islet Autoimmunity (ENDIA) longitudinal prospective pregnancy to childhood cohort study of Australian children at risk of type 1 diabetes: parental demographics and birth information. BMJ Open Diabetes Research & Care. 2024;12(4):10.1136/bmjdrc-2024-004130

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