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Technologies
  • Diagnostics
  • Clinical trials
  • Cohort studies
  • Cohort analysis

About

Our lab’s vision is to develop an interdisciplinary approach to dementia research and care.

Dementia is a complex condition that crosses a number of clinical and scientific disciplines. We understand that a strong, multifaceted approach is required to make a significant impact in dementia research. This includes having a long-term coordinated approach to research.

The focus of our lab is to:

  • Improve dementia diagnosis using novel and established biomarkers
  • Investigate midlife risk factors that may better inform prevention strategies
  • Establish and support dementia cohorts
  • Facilitate investigator-led clinical trials
  • Support and develop access to dementia research for regional and rural Australians
  • Investigate and address caregiver needs
  • Mentor the next generation of dementia clinical researchers

Publications

Selected publications from A/Prof Nawaf Yassi

Pavlin‐Premrl D, Waters M, Thijs V, Mitchell PJ, Yassi N, Parsons MW, Weir L, Pesavento L, Maingard J, Cloud G, Stanislaus V, Ngun M, Campbell BCV. Symptomatic Intracranial Atherosclerosis in an Australian Context: Common and Underdiagnosed in Multiple Ethnic Groups. Stroke Vascular and Interventional Neurology. 2025;5(1):10.1161/svin.124.001397

Wrigley S, Cody R, Amadoru S, Huynh A, Galante O, Mandrawa C, Yassi N, Yates P. Prevalence and associations of cerebral microbleeds in an Australian memory clinic cohort. Internal Medicine Journal. 2024;:10.1111/imj.16614

Yassi N, Yogendrakumar V, Churilov L, Meretoja A, Wu T, Campbell BCV, Strbian D, Jeng J-S, Woodhouse LJ, Ovesen C, Law ZK, Gu H-Q, Nie X, Liu J, Ma HH, Zhao H, Bath PM, Liu L, Sprigg N, Donnan GA, Davis SM. Tranexamic Acid Within 4.5 Hours of Intracerebral Hemorrhage With the CTA Spot Sign. Neurology. 2024;103(12):10.1212/wnl.0000000000210104

Eratne D, Kang MJY, Lewis C, Dang C, Malpas C, Ooi S, Brodtmann A, Darby D, Zetterberg H, Blennow K, Berk M, Dean O, Bousman C, Thomas N, Everall I, Pantelis C, Wannan C, Cicognola C, Hansson O, Janelidze S, Santillo AF, Velakoulis D, Group TMS. Plasma neurofilament light outperforms glial fibrillary acidic protein in differentiating behavioural variant frontotemporal dementia from primary psychiatric disorders. Journal of the Neurological Sciences. 2024;467:10.1016/j.jns.2024.123291

Kataike VM, Desmond PM, Steward C, Mitchell PJ, Davey C, Yassi N, Bivard A, Parsons MW, Campbell BCV, Ng F, Venkatraman V. Iron changes within infarct tissue in ischemic stroke patients after successful reperfusion quantified using QSM. Neuroradiology. 2024;66(12):10.1007/s00234-024-03444-6

Holper S, Loveland PM, Churilov L, Italiano D, Watson R, Yassi N. Blood astrocyte biomarkers in AD: a systematic review and meta‐analysis. Alzheimer’s & Dementia. 2024;20(Suppl 2):10.1002/alz.090544

Rosenich E, Pirotta S, Cummins H, Norfolk M, Da Costa G, Yassi N, Churilov L, Sinnott RO, Brodtmann A, Pase MP, Barton C, Bush AI, Maruff P, Ayton D, Lim YY, Group BR. Baseline demographic, risk and cognitive characteristics of the final randomized sample enrolled in a decentralised multi‐domain lifestyle intervention trial (BetterBrains) to delay cognitive decline. Alzheimer’s & Dementia. 2024;20(Suppl 7):10.1002/alz.090564

Bhalala OG, Beamish J, Summerell P, Porter T, Laws SM, Kang M, Huq A, Eratne D, Walterfang M, Farrand S, Evans AH, Kelso W, Watson R, Yassi N, Velakoulis D, Loi SM. Multi‐omic blood biomarkers and cognitive profiles discriminate causes of younger‐onset neurocognitive symptoms: a cohort study. Alzheimer’s & Dementia. 2024;20(Suppl 2):10.1002/alz.085786

Yogendrakumar V, Balabanski AH, Johns H, Churilov L, Parsons NK, Beharry J, Weir L, Yassi N, Zhao H, Warwick A, Coote S, Langenberg F, Branagan L, Siddiqi W, Bivard A, Campbell BCV, Donnan GA, Davis SM, Mutimer C, Barker J, Santos AD, Ng JL, Ng F, Yan B, Ma M, Wong J, Park A, Sharobeam A, Valente M, Williams C, Ho S, Scarff P, Beltrame C, Shin C, Thijs V, Fink J, Barber A, Lin L. Evaluating the Safety and Efficacy of Telemedicine Physician Assessments on a Mobile Stroke Unit: Protocol for a Prospective Open-Label Blinded End-Point Randomized Controlled Trial.Journal of the American Heart Association. 2024;13(21):10.1161/jaha.124.036856

Sorby-Adams AJ, Marian OC, Bilecki IM, Elms LE, Yassi N, Hood RJ, Coller JK, Stuckey SM, Kimberly WT, Farr TD, Leonard AV, Thornton E, Vink R, Turner RJ. NK1 tachykinin receptor antagonist treatment reduces cerebral edema and intracranial pressure in an ovine model of ischemic stroke. Cerebrovascular and Brain Metabolism Reviews. 2024;44(10):10.1177/0271678×241241907

Lab research projects

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