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About

Our lab’s vision is to develop an interdisciplinary approach to dementia research and care.

Dementia is a complex condition that crosses a number of clinical and scientific disciplines. We understand that a strong, multifaceted approach is required to make a significant impact in dementia research. This includes having a long-term coordinated approach to research.

The focus of our lab is to:

  • improve dementia diagnosis using novel and established biomarkers
  • investigate midlife risk factors that may better inform prevention strategies
  • establish and support dementia cohorts
  • facilitate investigator-led clinical trials
  • support and develop access to dementia research for regional and rural Australians
  • investigate and address caregiver needs
  • mentor the next generation of dementia clinical researchers

 

Publications

Selected publications from A/Prof Nawaf Yassi

1. Yassi N, Pase MP, Buckley RF, Rosenich E, Watson R, Maruff P, Lim YY. Cardiovascular Risk is Associated with Poorer Memory in Middle-aged Adults from the Healthy Brain Project. Journal of Alzheimer’s Disease. 2022. PMID: please insert

2. Kaffenberger T, Venkatraman V, Steward C, Thijs VN, Bernhardt J, Desmond PM, Campbell BCV, Yassi N. Stroke population-specific neuroanatomical CT-MRI brain atlas. Neuroradiology. 2022 PMID: 35094103

3. Yassi N, Zhao H, Churilov L, Campbell BCV, Wu T, Ma H, Cheung A, Kleinig T, Brown H, Choi P, Jeng JS, Ranta A, Wang HK, Cloud GC, Grimley R, Shah D, Spratt N, Cho DY, Mahawish K, Sanders L, Worthington J, Clissold B, Meretoja A, Yogendrakumar V, Ton MD, Dang DP, Phuong NTM, Nguyen HT, Hsu CY, Sharma G, Mitchell PJ, Yan B, Parsons MW, Levi C, Donnan GA, Davis SM. Tranexamic acid for intracerebral haemorrhage within 2 hours of onset: protocol of a phase II randomized placebo-controlled double-blind multicentre trial. Stroke and Vascular Neurology 2021

4. N. Yassi, S. Hilal, Y. Xia, Y. Y. Lim, R. Watson, H. Kuijf, C. Fowler, P. Yates, P. Maruff, R. Martins, D. Ames, C. Chen, C. C. Rowe, V. L. Villemagne, O. Salvado, P. M. Desmond and C. L. Masters. Influence of Comorbidity of Cerebrovascular Disease and Amyloid-beta on Alzheimer’s Disease. J Alzheimers Dis. 2020 73 PMID: 31884485

5. N. Yassi, L. Flicker and B. C. V. Campbell. Brain frailty and small vessel disease for stroke outcome prediction: Are we there yet? Neurology. 2020 94 PMID: 31882525

6. B. C. V. Campbell, P. J. Mitchell, L. Churilov, N. Yassi, T. J. Kleinig, R. J. Dowling, B. Yan, S. J. Bush, V. Thijs, R. Scroop, M. Simpson, M. Brooks, H. Asadi, T. Y. Wu, D. G. Shah, T. Wijeratne, H. Zhao, F. Alemseged, F. Ng, P. Bailey, H. Rice, L. de Villiers, H. M. Dewey, P. M. C. Choi, H. Brown, K. Redmond, D. Leggett, J. N. Fink, W. Collecutt, T. Kraemer, M. Krause, D. Cordato, D. Field, H. Ma, B. O’Brien, B. Clissold, F. Miteff, A. Clissold, G. C. Cloud, L. E. Bolitho, L. Bonavia, A. Bhattacharya, A. Wright, A. Mamun, F. O’Rourke, J. Worthington, A. A. Wong, C. R. Levi, C. F. Bladin, G. Sharma, P. M. Desmond, M. W. Parsons, G. A. Donnan, S. M. Davis and E.-I. T. P. investigators. Effect of Intravenous Tenecteplase Dose on Cerebral Reperfusion Before Thrombectomy in Patients With Large Vessel Occlusion Ischemic Stroke: The EXTEND-IA TNK Part 2 Randomized Clinical Trial. JAMA. 2020 PMID: 32078683

7. H. Ma, B. C. V. Campbell, M. W. Parsons, L. Churilov, C. R. Levi, C. Hsu, T. J. Kleinig, T. Wijeratne, S. Curtze, H. M. Dewey, F. Miteff, C. H. Tsai, J. T. Lee, T. G. Phan, N. Mahant, M. C. Sun, M. Krause, J. Sturm, R. Grimley, C. H. Chen, C. J. Hu, A. A. Wong, D. Field, Y. Sun, P. A. Barber, A. Sabet, J. Jannes, J. S. Jeng, B. Clissold, R. Markus, C. H. Lin, L. M. Lien, C. F. Bladin, S. Christensen, N. Yassi, G. Sharma, A. Bivard, P. M. Desmond, B. Yan, P. J. Mitchell, V. Thijs, L. Carey, A. Meretoja, S. M. Davis, G. A. Donnan and E. Investigators. Thrombolysis Guided by Perfusion Imaging up to 9 Hours after Onset of Stroke. N Engl J Med. 2019 380 PMID: 31067369

8. Y. Y. Lim, N. Yassi, L. Bransby, M. Properzi and R. Buckley. The Healthy Brain Project: An Online Platform for the Recruitment, Assessment, and Monitoring of Middle-Aged Adults at Risk of Developing Alzheimer’s Disease. J Alzheimers Dis. 2019 68 PMID: 30909237

9. B. C. V. Campbell, P. J. Mitchell, L. Churilov, N. Yassi, T. J. Kleinig, R. J. Dowling, B. Yan, S. J. Bush, H. M. Dewey, V. Thijs, R. Scroop, M. Simpson, M. Brooks, H. Asadi, T. Y. Wu, D. G. Shah, T. Wijeratne, T. Ang, F. Miteff, C. R. Levi, E. Rodrigues, H. Zhao, P. Salvaris, C. Garcia-Esperon, P. Bailey, H. Rice, L. de Villiers, H. Brown, K. Redmond, D. Leggett, J. N. Fink, W. Collecutt, A. A. Wong, C. Muller, A. Coulthard, K. Mitchell, J. Clouston, K. Mahady, D. Field, H. Ma, T. G. Phan, W. Chong, R. V. Chandra, L. A. Slater, M. Krause, T. J. Harrington, K. C. Faulder, B. S. Steinfort, C. F. Bladin, G. Sharma, P. M. Desmond, M. W. Parsons, G. A. Donnan, S. M. Davis and E.-I. T. Investigators. Tenecteplase versus Alteplase before Thrombectomy for Ischemic Stroke. N Engl J Med. 2018 378 PMID: 35135319

10. B. C. Campbell, P. J. Mitchell, T. J. Kleinig, H. M. Dewey, L. Churilov, N. Yassi, B. Yan, R. J. Dowling, M. W. Parsons, T. J. Oxley, T. Y. Wu, M. Brooks, M. A. Simpson, F. Miteff, C. R. Levi, M. Krause, T. J. Harrington, K. C. Faulder, B. S. Steinfort, M. Priglinger, T. Ang, R. Scroop, P. A. Barber, B. McGuinness, T. Wijeratne, T. G. Phan, W. Chong, R. V. Chandra, C. F. Bladin, M. Badve, H. Rice, L. de Villiers, H. Ma, P. M. Desmond, G. A. Donnan, S. M. Davis and Extend-IA Investigators. Endovascular therapy for ischemic stroke with perfusion-imaging selection. N Engl J Med. 2015 372

Lab research projects

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