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Technologies
  • Diagnostics
  • Clinical trials
  • Cohort studies
  • Cohort analysis
Themes / Divisions

About

Our lab’s vision is to develop an interdisciplinary approach to dementia research and care.

Dementia is a complex condition that crosses a number of clinical and scientific disciplines. We understand that a strong, multifaceted approach is required to make a significant impact in dementia research. This includes having a long-term coordinated approach to research.

The focus of our lab is to:
– Improve dementia diagnosis using novel and established biomarkers
– Investigate midlife risk factors that may better inform prevention strategies
– Establish and support dementia cohorts
– Facilitate investigator-led clinical trials
– Support and develop access to dementia research for regional and rural Australians
– Investigate and address caregiver needs
– Mentor the next generation of dementia clinical researchers

Publications

Selected publications from A/Prof Nawaf Yassi

Kataike VM, Desmond PM, Steward C, Mitchell PJ, Davey C, Yassi N, Bivard A, Parsons MW, Campbell BCV, Ng F, Venkatraman V. Iron changes within infarct tissue in ischemic stroke patients after successful reperfusion quantified using QSM. Neuroradiology. 2024;:10.1007/s00234-024-03444-6

Holper S, Loveland P, Churilov L, Italiano D, Watson R, Yassi N. Blood Astrocyte Biomarkers in Alzheimer Disease. Neurology. 2024;103(3):10.1212/wnl.0000000000209537

Mujanovic A, Ng FC, Branca M, Deutschmann HA, Meinel TR, Churilov L, Nistl O, Mitchell PJ, Yassi N, Parsons MW, Sharma GJ, Gattringer T, Arnold M, Cavalcante F, Piechowiak EI, Kleinig TJ, Seiffge DJ, Dobrocky T, Gralla J, Fischer U, Kneihsl M, Campbell BCV, Kaesmacher J. External Validation of a Model for Persistent Perfusion Deficit in Patients With Incomplete Reperfusion After Thrombectomy. Neurology. 2024;103(2):10.1212/wnl.0000000000209401

Dobson H, Al Maawali S, Malpas C, Santillo AF, Kang M, Todaro M, Watson R, Yassi N, Blennow K, Zetterberg H, Foster E, Neal A, Velakoulis D, O’Brien TJ, Eratne D, Kwan P. Elevated plasma neurofilament light and glial fibrillary acidic protein in epilepsy versus nonepileptic seizures and nonepileptic disorders. Epilepsia. 2024;:10.1111/epi.18065

Bhalala OG, Thompson J, Watson R, Yassi N. Contextualising the benefits and risks of anti‐amyloid therapy for patients with Alzheimer disease and their care team. The Medical Journal of Australia. 2024;221(2):10.5694/mja2.52359

Mutimer CA, Yassi N, Wu TY. Blood Pressure Management in Intracerebral Haemorrhage: when, how much, and for how long?. Current Neurology and Neuroscience Reports. 2024;24(7):10.1007/s11910-024-01341-2

Bransby L, Yassi N, Rosenich E, Buckley R, Li Q-X, Maruff P, Pase M, Lim YY. Associations between multidomain modifiable dementia risk factors with AD biomarkers and cognition in middle-aged and older adults. Neurobiology of Aging. 2024;138:10.1016/j.neurobiolaging.2024.02.015

Yassi N, Zhao H, Churilov L, Wu TY, Ma H, Nguyen H-T, Cheung A, Meretoja A, Ton D, Kleinig T, Jeng J-S, Choi PMC, Duc PD, Brown H, Ranta A, Spratt N, Cloud GC, Wang H-K, Grimley R, Mahawish K, Cho D-Y, Shah D, Nguyen TMP, Sharma G, Yogendrakumar V, Yan B, Harrison EL, Devlin M, Cordato D, Martinez-Majander N, Strbian D, Thijs V, Sanders LM, Anderson D, Parsons MW, Campbell BCV, Donnan GA, Davis SM, Investigators S-MT. Tranexamic acid versus placebo in individuals with intracerebral haemorrhage treated within 2 h of symptom onset (STOP-MSU): an international, double-blind, randomised, phase 2 trial. The Lancet Neurology. 2024;23(6):10.1016/s1474-4422(24)00128-5

Cavuoto MG, Davies L, Rowsthorn E, Cribb LG, Yiallourou SR, Yassi N, Maruff P, Lim YY, Pase MP. Cross-sectional associations between neighborhood characteristics, cognition and dementia risk factor burden in middle-aged and older Australians. Preventive Medicine Reports. 2024;41:10.1016/j.pmedr.2024.102696

Yogendrakumar V, Beharry J, Churilov L, Pesavento L, Alidin K, Ugalde M, Weir L, Mitchell PJ, Kleinig TJ, Yassi N, Thijs VN, Wu TY, Brown H, Dewey HM, Wijeratne T, Yan B, Sharma GJ, Desmond P, Parsons MW, Donnan GA, Davis SM, Campbell BCV. Association of Time to Thrombolysis With Early Reperfusion After Alteplase and Tenecteplase in Patients With Large Vessel Occlusion.Neurology. 2024;102(7):10.1212/wnl.0000000000209166

Lab research projects

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