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About

I am a medical oncologist with a special interest in colorectal cancer.

My research is aimed at understanding the features of colorectal cancer that predict how a patient will experience the disease, such as whether they will respond to therapy and whether they are at risk of recurrence following surgery.

I am also exploring whether a simple blood test could be used for the early detection of cancer, diagnosing tumours before they spread, when the chance of cure is high.

Publications

Selected publications from Prof Jeanne Tie

Dunn C, Tie J, Gibbs P. A Call for Improved Guidance to Integrate Modern Biomarkers Into Routine Clinical Care—Piecing the Puzzle Together. JAMA Oncology. 2025;11(4):10.1001/jamaoncol.2024.6479

Piercey O, Chantrill L, Hsu H, Ma B, Price T, Tan IB, Teng H, Tie J, Desai J. Expert consensus on the optimal management of BRAFV600E‐mutant metastatic colorectal cancer in the Asia‐Pacific region. Asia-Pacific Journal of Clinical Oncology. 2025;21(1):10.1111/ajco.14132

Hitchen N, Wong H-L, Wong R, Shapiro JD, Burge ME, Nott LM, Lee B, Lim SH-S, Wong SF, Caird S, Wong V, Rainey NH, Khattak A, Mandaliya HA, Hayes TM, Torres J, Jalali A, Campbell A, Gibbs P, Tie J. Real world characteristics and outcomes of patients with BRAFV600E-mutant metastatic colorectal cancer in Australia: The COALA project.Journal of Clinical Oncology. 2025;43(4_suppl):10.1200/jco.2025.43.4_suppl.70

Hitchen N, Shahnam A, Tie J. Circulating Tumor DNA: A Pan-Cancer Biomarker in Solid Tumors with Prognostic and Predictive Value. Annual Review of Medicine. 2025;76(1):10.1146/annurev-med-100223-090016

Loft M, Wong V, Kosmider S, Wong R, Shapiro J, Hong W, Jennens R, Tie J, Caird S, Steel S, Lee B, Nott L, Khattak MA, Lim S, Chong G, Hayes T, Underhill C, McLachlan S, Rainey N, Dunn C, Gibbs P. Real‐world impact of pembrolizumab availability for deficient mismatch repair metastatic colorectal cancer. Internal Medicine Journal. 2025;55(1):10.1111/imj.16575

Burge ME, Espinoza D, Sjoquist KM, Siu DH, Mercieca-Bebber R, Chantrill LA, Karapetis CS, Steer CB, Yip S, Cuff J, Winata S, Tie J, Thaker DA, Srivastav R, Abdi E, Strickland A, Segelov E, Francesconi A, Price T, Ladwa R, Joubert W, Tebbutt NC. AGITG MONARCC: A randomized phase 2 study of panitumumab monotherapy and panitumumab plus 5-Fluorouracil as first-line therapy for older patients with RAS and BRAF wild type metastatic colorectal cancer. A study by the Australasian Gastro-Intestinal Trials Group (AGITG). Clinical Colorectal Cancer. 2024;:10.1016/j.clcc.2024.11.003

Muhandiramge J, Zalcberg JR, Warner ET, Polekhina G, Gibbs P, van Londen GJ, Bernstein WB, Macrae F, Haydon A, Tie J, Millar JL, Mar VJ, Gately L, Tonkin A, Ford L, Umar A, Chan AT, Woods RL, Orchard SG. Cardiovascular disease and stroke following cancer and cancer treatment in older adults. Cancer. 2024;130(23):10.1002/cncr.35503

Glewis S, Lingaratnam S, Lee B, Campbell I, IJzerman M, Fagery M, Harris S, Georgiou C, Underhill C, Warren M, Campbell R, Jayawardana M, Silva SSM, Martin JH, Tie J, Alexander M, Michael M. Pharmacogenetic‐guided dosing for fluoropyrimidine (DPYD) and irinotecan (UGT1A1*28) chemotherapies for patients with cancer (PACIFIC‐PGx): A multicenter clinical trial. Clinical and Translational Science. 2024;17(12):10.1111/cts.70083

Tie J. Abstract IA017: ctDNA based detection of MRD in colon cancer: Towards clinical implementation. Clinical Cancer Research. 2024;30(21_Supplement):10.1158/1557-3265.liqbiop24-ia017

Allan Z, Wang Y, Tie J, Tebbutt N, Clemons N, Papadopoulos N, Kinzler K, Vogelstein B, Liu DS. Abstract A049: Peritoneal tumor DNA as a prognostic biomarker in locally advanced gastroesophageal cancer: A pilot prospective cohort study. Clinical Cancer Research. 2024;30(21_Supplement):10.1158/1557-3265.liqbiop24-a049

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