Calleja DJ, Kuchel N, Lu BGC, Birkinshaw RW, Klemm T, Doerflinger M, Cooney JP, Mackiewicz L, Au AE, Yap YQ, Blackmore TR, Katneni K, Crighton E, Newman J, Jarman KE, Call MJ, Lechtenberg BC, Czabotar PE, Pellegrini M, Charman SA, Lowes KN, Mitchell JP, Nachbur U, Lessene G, Komander D. Insights Into Drug Repurposing, as Well as Specificity and Compound Properties of Piperidine-Based SARS-CoV-2 PLpro Inhibitors. Frontiers in Chemistry. 2022;10:10.3389/fchem.2022.861209
Klemm T, Ebert G, Calleja DJ, Allison CC, Richardson LW, Bernardini JP, Lu BG, Kuchel NW, Grohmann C, Shibata Y, Gan ZY, Cooney JP, Doerflinger M, Au AE, Blackmore TR, van der Heden van Noort GJ, Geurink PP, Ovaa H, Newman J, Riboldi‐Tunnicliffe A, Czabotar PE, Mitchell JP, Feltham R, Lechtenberg BC, Lowes KN, Dewson G, Pellegrini M, Lessene G, Komander D. Mechanism and inhibition of the papain‐like protease, PLpro, of SARS‐CoV‐2. The EMBO Journal. 2020;39(18):10.15252/embj.2020106275
Bond S, Draffan AG, Fenner JE, Lambert J, Lim CY, Lin B, Luttick A, Mitchell JP, Morton CJ, Nearn RH, Sanford V, Stanislawski PC, Tucker SP. The discovery of 1,2,3,9b-tetrahydro-5H-imidazo[2,1-a]isoindol-5-ones as a new class of respiratory syncytial virus (RSV) fusion inhibitors. Part 1. Bioorganic & Medicinal Chemistry Letters. 2015;25(4):10.1016/j.bmcl.2014.11.018
Bond S, Draffan AG, Fenner JE, Lambert J, Lim CY, Lin B, Luttick A, Mitchell JP, Morton CJ, Nearn RH, Sanford V, Anderson KH, Mayes PA, Tucker SP. 1,2,3,9b-Tetrahydro-5H-imidazo[2,1-a]isoindol-5-ones as a new class of respiratory syncytial virus (RSV) fusion inhibitors. Part 2: Identification of BTA9881 as a preclinical candidate. Bioorganic & Medicinal Chemistry Letters. 2015;25(4):10.1016/j.bmcl.2014.11.024
Stokes NR, Baker N, Bennett JM, Chauhan PK, Collins I, Davies DT, Gavade M, Kumar D, Lancett P, Macdonald R, MacLeod L, Mahajan A, Mitchell JP, Nayal N, Nayal YN, Pitt GRW, Singh M, Yadav A, Srivastava A, Czaplewski LG, Haydon DJ. Design, synthesis and structure–activity relationships of substituted oxazole–benzamide antibacterial inhibitors of FtsZ. Bioorganic & Medicinal Chemistry Letters. 2014;24(1):10.1016/j.bmcl.2013.11.002
Stokes NR, Baker N, Bennett JM, Berry J, Collins I, Czaplewski LG, Logan A, Macdonald R, MacLeod L, Peasley H, Mitchell JP, Nayal N, Yadav A, Srivastava A, Haydon DJ. An Improved Small-Molecule Inhibitor of FtsZ with Superior In Vitro Potency, Drug-Like Properties, and In Vivo Efficacy. Antimicrobial Agents and Chemotherapy. 2013;57(1):10.1128/aac.01580-12
Lambert JN, Mitchell JP, Roberts KD. ChemInform Abstract: The Synthesis of Cyclic Peptides. ChemInform. 2001;32(31):10.1002/chin.200131244
Lambert JN, Mitchell JP, Roberts KD. The synthesis of cyclic peptides. Journal of the Chemical Society Perkin Transactions 1. 2001;(5):10.1039/b001942i
Mitchell JP, Roberts KD, Langley J, Koentgen F, Lambert JN. A direct method for the formation of peptide and carbohydrate dendrimers. Bioorganic & Medicinal Chemistry Letters. 1999;9(19):10.1016/s0960-894x(99)00480-1
