Lucet Lab: Kinase Signalling and Drug Discovery

Our lab is committed to investigating the root causes of diseases and developing cutting-edge therapeutic strategies that can enhance the health of our community. We are primarily focused on understanding the role of proteins in cellular processes and how their malfunction can lead to the onset of diseases such as cancer, autoimmune disorders, and neurological conditions.

We specifically study protein kinases, which are signaling proteins that regulate nearly all biological processes in the body. Through our research, we aim to uncover novel kinase-driven signaling pathways and identify the mechanisms that contribute to uncontrolled signaling, which can cause cancer and inflammatory disorders.

Our ultimate goal is to leverage our fundamental research findings to create innovative therapeutic approaches that can effectively prevent and treat diseases caused by kinase dysregulation. We are confident that our expertise and knowledge will make a significant impact on the health and well-being of our community.

As a lab, we rely on the crucial support of basic research funding to translate our findings into practical applications and accelerate the development of groundbreaking treatments.

Our mission is to unravel the complexities of protein kinase signalling networks and harness this knowledge to pioneer innovative therapies. We aim to bridge the gap between fundamental kinase biology and clinical applications, focusing on understanding non-catalytic signalling functions, developing targeted treatments, and advancing precision medicine.

Through multidisciplinary approaches and cutting-edge techniques, including structural biology, advanced imaging, and chemical biology, we strive to translate our discoveries into novel diagnostics and therapeutics for aggressive cancers, inflammatory conditions, and neurological disorders.

By collaborating with experts from various fields and partnering with industry, we accelerate the discovery of cutting-edge therapies, ultimately improving patient outcomes and community health

Our research has significantly advanced the field of kinase biology and drug discovery. We have successfully:

1. Identified novel kinase targets and mechanisms in disease pathways
2. Developed innovative structure-based discovery methods
3. Provided key insights into counteracting kinase-driven diseases
4. Accelerated the translation of basic research into clinical applications

Through our industry collaborations, we’ve bridged the gap between academic findings and commercial drug development, leading to promising therapeutic candidates. Our work has resulted in impact publications and new research tools, contributing to the global scientific community and paving the way for improved treatments in cancer, inflammatory conditions, and neurological disorders.