Lucet-Publications

Lucet-Publications

Researcher: 

Selected publications

  1. Liu L, Phua YW, Lee RS, Ma X, Jenkins Y, Novy K, Humphrey ES, Chan H, Shearer R, Ong PC, Dai W, Saunders DN, Lucet IS, Daly RJ. (2016) Homo- and heterotypic association regulates signaling by the SgK269/PEAK1 and SgK223 pseudokinases. J Biol Chem, (291) 41, 7 October 2016, 21571-21583.
  2. Prinz B, Harvey KL, Wilcke L, Ruch U, Engelberg K, Biller L, Lucet I, Erkelenz S, Heincke D, Spielmann T, Doerig C, Kunick C, Crabb BS, Gilson PR, Gilberger TW, Hierarchical phosphorylation of apical membrane antigen 1 is required for efficient red blood cell invasion by malaria parasites. Sci Reports. 2016 Volume 6, Article number 34479 PMCID: PMC5048298
  3. Chen K, Dobson RCJ, Lucet IS, Young SN, Pearce FG, Blewitt ME, Murphy JM. The epigenetic regulator smchd1 contains a functional ghkl-type atpase domain. J Biol Chem, 2016 473(12), 1733-1744. PMID: 27059856
  4. Patel O, Dai W, Mentzel M, Griffin MD, Serindoux J, Gay Y, Fischer S, Sterle S, Kropp A, Burns CJ, Ernst M, Buchert M, Lucet IS. Biochemical and structural insights in Doublecortin-like Kinase Domain 1. Structure. 2016 6;24(9): 1550-61. PMID: 27545623
  5. Jacobsen AV, Lowes KN, Tanzer MC, Lucet IS, Hildebrand JM, Petrie EJ, Van Delft MF, Liu Z, Conos SA, Zhang JG, Huang DCS, Silke J, Lessene G, Murphy JM. HSP90 activity is required for MLKL oligomerisation and membrane translocation and the induction of necroptotic cell. Cell Death Dis., 2016, 7, e2051. PMID: 26775703
  6. Murphy JM, Nakatani Y, Jamieson SA, Dai W, Lucet IS, Mace PD. Molecular mechanism of CCAAT-enhancer binding protein recruitment by the TRIB1 pseudokinase. Structure. 2015 23(11):2111-2121. PMID: 26455797
  7. Chen K, Hu J, Moore DL, Liu R, Kessans SA, Breslin K, Lucet IS, Keniry A, Leong HS, Parish CL, Hilton DJ, Lemmers RJ, van der Maarel SM, Czabotar PE, Dobson RC, Ritchie ME, Kay GF, Murphy JM, Blewitt ME. Genome-wide binding and mechanistic analyses of Smchd1-mediated epigenetic regulation. Proc Natl Acad Sci U S A. 2015 112(27):E3535-3544. PMID: 26091879
  8. Hildebrand JM, Lucet IS, Murphy JM. (2015) Flicking the molecular switch underlying MLKL-mediated necroptosis. Mol Cell Oncol. 23;2(3):e985550. PMID: 27308464
  9. Murphy JM, Zhang Q, Young SN, Reese ML, Bailey FP, Eyers PA, Ungureanu D, Hammaren H, Silvennoinen O, Varghese LN, Chen K, Tripaydonis A, Jura N, Fukuda K, Qin J, Nimchuk Z, Mudgett MB, Elowe S, Gee CL, Liu L, Daly RJ, Manning G, Babon JJ, Lucet IS. A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties. Biochem J. 2014 Jan 15;457(2):323-34. PMID: 24107129
  10. Babon JJ, Lucet IS, Murphy JM, Nicola NA, Varghese LN. The molecular regulation of Janus kinase (JAK) activation. Biochem J. 2014 Aug 15;462(1):1-13. PMID: 25057888

 

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