Selected publications

1. Ashton, T. D.; Dans, M.G.; Favuzza, P.; Ngo, A.; Lehane, A. M.; Zhang, X.; Qiu, D.; Chandra Maity, B.; De, N.; Schindler, K.A.; Yeo, T.; Park, H.; Uhleman, A.-C.; Churchyard, A.; Baum, J.; Fidock, D.A.; Jarman, K.E.; Lowes, K. N.; Baud, D.; Brand, S.; Jackson, P. F.; Cowman, A. F.; Sleebs, B. E. Optimization of 2,3-dihydroquinazoline-3-carboxamides as antimalarials targeting PfATP4. J. Med. Chem. 2023, PMID: 36812492 
2. Nguyen, W.; Dans, M. G.; Currie, I.; Awalt, J. K.; Bailey, B. L.; Lumb, C.; Ngo, A.; Favuzza, P.; Palandri, J.; Ramesh, S.; Penington, J. S.; Jarman, K. E.; Mukherjee, P.; Chakraborty, A.; Maier, A. G.; van Dooren, G. G.; Papenfuss, T.; Wittlin, S.; Churchyard, A.; Baum, J.; Winzeler, E.A.; Baud, D.; Brand, S.; Jackson, P. F.; Cowman, A. F.; Sleebs, B. E. ACS Infect. Dis. 2023, PMID: 36853190 
3. Chen H.; Nguyen, N.; Magtoto, C; Cobbold, S.; Richardson, L. W.; Meza, L.; Au, A.; Corbin, J.; Lechtenberg, B.; Sutherland, K.; Feltham, B.; Grohmann, C.; Nicholson, S. N.; Sleebs, B. E. Design and characterization of a heterobifunctional degrader of KEAP1. Redox. Biol. 2023, 59, 102552. PMID: 36473314 
4. Chen H.; Li, K.; Wu, Y.; Currie, I.; Keating, N.; Dehkhoda, F.; Grohmann, C.; Babon, J. J.; Nicholson, S. N.; Sleebs, B. E. Optimization of phosphotyrosine peptides that bind to the SH2 domain of SOCS1 and block substrate ubiquitination. ACS Chem. Biol. 2022, 17(2), 449–462. PMID: 34989544 
5. Nguyen, W.; Dans, M. G.; Ngo, A.; Gancheva, M. R.; Romeo, O.; Duffy, S.; de Koning-Ward, T. F.; Lowes, K. N.; Jousset Sabroux, H.; Avery, V. M.; Wilson, D. W.; Gilson, P.R.; Sleebs, B.E. Structure activity refinement of phenylsulfonyl piperazines as antimalarials that block erythrocytic invasion. Eur. J. Med. Chem. 2021, 214, 113253. PMID: 33610028 
6.  Nguyen, W.; Lee, E. F.; Evangelista, M.; Lee, M.; Harris, T. J.; Colman, P. M.; Williams, L. B.; Smith, N.; Lowes, K. N.; Haeberli, C.; Keiser, J.; Smith, B. J.; Fairlie, D. W. Sleebs, B. E. Optimization of benzothiazole and thiazole hydrazones as inhibitors of schistosome BCL-2. ACS Infect. Dis. 2021, 7(5) 1143-1163. PMID: 33523649 
7. Currie, I.; Sleebs, B. E. Synthesis of acyl phosphoramidates via a modified Staudinger reaction. Org. Lett. 2021, 23(2) 464-468. PMID: 33379864 
8. Chen H.; Mao R.; Brzozowski, M; Nguyen, N.; Sleebs, B. E. Late stage phosphotyrosine mimetic functionalization of peptides employing a nickel-catalyzed photoredox cross-coupling. Org. Lett. 2021, 23, 11, 4244-4249. PMID: 34029466 
9. Bailey, B. L.; Nguyen, W.; Ngo, A.; Goodman, C. D.; Gancheva, M. R.; Favuzza, P.; Sanz, L. M.; Gamo, F-J.; Lowes, K. N.; McFadden, G. I.; Wilson, D. W.; Laleu, B.; Brand S.; Jackson, P. F.; Cowman, A. F.; Sleebs, B. E. Optimization of 2-(N-phenyl carboxamide) triazolopyrimidine antimalarials with moderate to slow acting erythrocytic stage activity. Bioorg. Chem. 2021, 115, 105244. PMID: 34452759 
10. Nguyen, W.; Jacobson, J.; Jarman, K. E.; Blackmore, T. R.; Jousset Sabroux, H.; Lewin, S. R.; Purcell, D. F.; Sleebs, B. E. Optimization of 5-substituted thiazolyl ureas and 6-substituted imidazolopyridines as potential HIV-1 latency reversing agents. Eur. J. Med. Chem. 2020, 195, 112254. PMID: 32109369 

Further publications