Advancing precision medicine for Parkinson’s

To understand Parkinson’s causes, diverse presentation and complexity.

To establish a network of linked Movement Disorder Clinics, initially in Victoria, New South Wales and Tasmania, to share patient biosamples and data using a standardised protocol to include longitudinal sampling, clinical progression, UPDRS, clinical neurological function examinations and consideration to environmental factors.

• Dr Andrew Evans, Royal Melbourne Hospital
• Professor Carolyn Sue, Neuroscience Research Australia
• Professor Jane Alty, University of Tasmania
• Dr Niro Vijiaratnam, Monash University

This project aims to deliver alignment between clinical and biological subtypes of Parkinson’s through a connected network of clinics using a standardised protocol.

We aim to develop the use of artificial intelligence as a complement to clinical measures, such as the UPDRS to provide a platform for data and sample sharing (including prodromal Parkinson’s) to aid the discovery of biomarkers for the subtypes.

Ultimately this project will determine the biological mechanisms behind the progression of Parkinson’s in these new biologically driven clinical subtypes.