Imaging biology in 4D has been a significant challenge in recent decades. The light used for imaging usually damages biological samples, making long term time-lapse microscopy extremely difficult.
Lattice light sheet microscopy is at the cutting edge of technology for live cell imaging because it is incredibly gentle on samples, allowing high resolution imaging over time.
This lattice light sheet was custom-built by staff at the Centre for Dynamic Imaging and was the first of its kind in Australia.