Professor Kelly Rogers has more than 20 years’ experience in advanced microscopy. Her strategic development of the Centre for Dynamic Imaging has enabled researchers to work at the cutting edge of discoveries in human biology.

Areas of expertise:

• Confocal microscopy
• Ca²⁺ imaging
• Lattice light sheet microscopy
• Super-resolution microscopy – 3D SIM
• Preclinical imaging – fluorescence, bioluminescence and micro-CT

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With a background in engineering and biology Dr Niall Geoghegan is responsible for developing WEHI’s lattice light sheet imaging capabilities.

Areas of expertise:

• Optical system design and engineering
• Lattice light sheet microscopy
• Confocal and widefield technology
• Time-resolved fluorescence methods: FCS, FLIM, FRAP
• Live cell imaging

Areas of expertise:

• Blood-stage malaria biology
• Live-cell imaging
• Lattice light sheet microscopy
• Molecular biology
• Drug screening

Dawson Ling’s key research interest lies in unravelling how the malaria parasite (Plasmodium falciparum) invades the human red blood cell. He joined the Centre for Dynamic Imaging group to continue working on blood-stage malaria invasion using state-of-the-art microscopy techniques, including lattice light sheet microscopy. He is developing novel imaging techniques, such as expansion microscopy of invading malaria parasites.

He completed his PhD and Honours at the Burnet Institute, where he investigated the mechanism of action of novel invasion-blocking compounds in blood-stage Plasmodium falciparum using a combination of approaches, including functional assays, molecular biology, mass spectrometry and live-cell imaging. During his PhD, he managed to uncover parasite proteins that are involved in invasion-related lipid metabolism/signalling. Previously, he supported clinical research trials as a Clinical Trials Assistant at the Melbourne Children’s Trials Centre (Murdoch’s Children Research Institute) and maintained food quality/assurance as an Analytical Chemist at BVAQ.

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Areas of Expertise:

• Bioimage Informatics
• Artificial intelligence and machine learning
• Imaging
• Spatial omics analysis
• Data Analysis and Visualisation

Pradeep joined the Centre for Dynamic Imaging at WEHI in 2021, and is a part of the Bioimage Analysis Core. He completed his PhD in Drug Discovery Biology at Monash Institute of Pharmaceutical Sciences (MIPS) in 2017. Pradeep enjoys working at the intersection of biology and computational methods.

These days, he is just as comfortable working with large tables as with wrangling large images. Pradeep is a passionate about open-source tools and making research software sustainable.

He is a lead developer of two software tools:

* napari-lattice: User-friendly workflows to process lattice lightsheet data

* Gut Analysis Toolbox: Software to help characterize the nervous system in the gut. Published in Journal of Cell Science (senior author).

He is also a reviewer for the Journal of Open Source Software (JOSS).

Dr Lachlan Whitehead has been instrumental in developing the centre’s image analysis capabilities. He works closely with researchers to produce data-rich visualisations of their studies.

Areas of expertise:

• Image analysis
• Software
• 3D design and printing
• Data visualization
• Data processing pipelines

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Areas of expertise:

• Spatial transcriptomics
• Hematological malignancy
• Breast cancer
• Bone marrow biology
• Developmental biology

Dr Raymond Yip is a Senior Research Officer at WEHI with joint appointments across the Imaging, Genomics, and Hawkins laboratories. His research project uses cutting-edge spatial transcriptomics technologies to study how myeloma cancer cells survive and evade therapy inside the bone marrow.

He co-leads WEHI’s spatial transcriptomics team and has extensive collaborations with academic groups and biotechnology companies.

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Areas of expertise:

• Image analysis
• Bioinformatics
• Spatial transcriptomics (MERSCOPE and Xenium)
• Machine-learning-based segmentation
• Whole-brain registration and analysis
• Tissue processing and imaging
• Neuroinflammation and host-pathogen interactions

Ishrat Zaman is a bioimage analyst and bioinformatician with experience in both wet-lab and dry-lab environments. She completed her Bachelor of Science with a major in Computational Biology from the University of Melbourne and completed her Honours at WEHI, investigating host neuroimmune and neuroinflammatory responses to Toxoplasma gondii infection. Her research integrated spatial transcriptomics, confocal, and lightsheet microscopy across both sectioned and whole-brain tissue. Currently, she is a member of the Bioimage Analysis Core, where she collaborates with scientists and biologists to process, visualise, and extract meaningful insights from complex imaging datasets through the development of tailored analysis tools and reproducible pipelines.

Areas of expertise:

• Advanced imaging and 3D/Confocal Microscopy
• Optical system design and engineering
• Single Objective Lightsheet Microscopy
• Laser microdissection
• 3D printing

Emma joined the Centre for Dynamic Imaging at WEHI in 2024 as a postdoctoral researcher and facility staff.

Her main area of research is to develop custom microscopes and trial new imaging techniques, including a single objective lightsheet microscope for fast, large field-of-view volumetric imaging. Her facility role includes training users, consulting on experimental design, coordinating equipment maintenance, and supporting daily operations.

Emma completed her PhD in 2024 at Swinburne University of Technology in the Sally McArthur 4D cell culture lab and the Paul Stoddart Applied Optics Lab. Her PhD was funded by the AFOSR Biophysics program and focused on developing imaging technologies for 4D cell culture. Emma has a background in physics having completed her Bachelor of Science(hons)/Master of Nanotechnology at La Trobe University, majoring in Physics, Mathematics, and Nanotechnology.

Areas of expertise:

• High-plex imaging (TOF-MS by MIBIscope, SeqIF by COMET)
• Laser microdissection
• Confocal and widefield microscopy
• Light sheet microscopy
• Preclinical imaging

Patrick Lam is a WEHI Imaging Lab member with broad expertise across the areas of histology, microscopy, and image analysis. Here at the Centre for Dynamic Imaging, he plays a key role in the set-up and ongoing maintenance of the state-of-the-art spatial proteomics imaging platforms. As demand from internal and external researchers grows, Patrick focuses on case-based protocol development, optimisation, and project coordination to help users generate high-quality unprecedented spatial data in a timely and cost-efficient manner. In his day-to-day role, he also supports instrumentation including operation, training, troubleshooting, and maintenance of a wide range of advanced microscopes within the facility.

Areas of expertise:

• Image analysis
• Bioinformatics
• Spatial proteomics (MIBIScope and Comet)
• Machine-learning-based segmentation
• Multiplex imaging analysis
• Multiclass cellular phenotyping

Michael Mckay is an Image Analyst in the Bioimage Analysis Core (BAC) of the Walter and Eliza Hall Institute of Medical Research (WEHI). His primary focus is on spatial proteomics, where he helps research scientists turn complex, multiplex imaging data into meaningful biological insights, particularly in the context of cancer and immune-related diseases.

Michael also regularly collaborates across research teams to support projects involving various imaging platforms, including Lattice light-sheet microscopy and brightfield imaging. He works extensively with Python for machine learning, deep learning, and image processing, and integrates other programming languages as needed for analysis. He also uses tools like QuPath and Nextflow, where he develops and maintains pipelines for multiplex image analysis. Passionate about bridging biology and computation, Michael enjoys testing and deploying the latest tools and workflows to make advanced image analysis more efficient and scalable

Areas of expertise:

• Spatial proteomics
• High-plex, advanced imaging and 3D confocal microscopy
• Light sheet microscopy
• Tissue processing and imaging
• Cardiovascular and bone marrow biology

Dr Emma Watson is a Senior Research Officer at WEHI where she leads WEHI’s Spatial Proteomics team in the Centre for Dynamic Imaging. Emma’s spatial proteomics work primarily uses the Lunaphore COMET multi-omics platform, where she develops targeted high-plex panels across multiple tissue types and the subsequent single-cell level image analysis. She also has expertise in highly multiplexed 3D tissue imaging and light sheet microscopy, applying these approaches to uncover the spatial organisation of complex biological systems.

She completed a PhD in vascular biology and cell death regulation, producing multiple high-impact, first author publications with a strong emphasis on imaging and analysis. She then undertook postdoctoral research at the Max Planck Institute for Molecular Biomedicine, where she in bone marrow vasculature and environment and was awarded a prestigious Alexander von Humboldt Fellowship in support of her work.