Cook ASI, Chen M, Nguyen TN, Cabezudo AC, Khuu G, Rao S, Garcia SN, Yang M, Iavarone AT, Ren X, Lazarou M, Hummer G, Hurley JH. Structural pathway for PI3-kinase regulation by VPS15 in autophagy. Science. 2025;:10.1126/science.adl3787
Schmuckli-Maurer J, Bindschedler AF, Wacker R, Würgler OM, Rehmann R, Lehmberg T, Murphy LO, Nguyen TN, Lazarou M, Monfregola J, Ballabio A, Heussler VT. Plasmodium berghei liver stage parasites exploit host GABARAP proteins for TFEB activation. Communications Biology. 2024;7(1):10.1038/s42003-024-07242-x
Adriaenssens E, Nguyen TN, Sawa-Makarska J, Khuu G, Schuschnig M, Shoebridge S, Skulsuppaisarn M, Watts EM, Csalyi KD, Padman BS, Lazarou M, Martens S. Control of mitophagy initiation and progression by the TBK1 adaptors NAP1 and SINTBAD. Nature Structural & Molecular Biology. 2024;31(11):10.1038/s41594-024-01338-y
Adriaenssens E, Schaar S, Cook ASI, Stuke JFM, Sawa-Makarska J, Nguyen TN, Ren X, Schuschnig M, Romanov J, Khuu G, Lazarou M, Hummer G, Hurley JH, Martens S. Reconstitution of BNIP3/NIX-mediated autophagy reveals two pathways and hierarchical flexibility of the initiation machinery. 2024;5(09-09):10.1101/2024.08.28.609967
Nguyen-Dien GT, Townsend B, Kulkarni PG, Kozul K-L, Ooi SS, Eldershaw DN, Weeratunga S, Liu M, Jones MJ, Millard SS, Ng DC, Pagano M, Bonfim-Melo A, Schneider T, Komander D, Lazarou M, Collins BM, Pagan JK. PPTC7 antagonizes mitophagy by promoting BNIP3 and NIX degradation via SCFFBXL4. EMBO Reports. 2024;25(8):10.1038/s44319-024-00181-y
Tudorica DA, Basak B, Cordova ASP, Khuu G, Rose K, Lazarou M, Holzbaur ELF, Hurley JH. A RAB7A phosphoswitch coordinates Rubicon Homology protein regulation of Parkin-dependent mitophagy. Journal of Cell Biology. 2024;223(7):10.1083/jcb.202309015
Saunders TL, Windley SP, Gervinskas G, Balka KR, Rowe C, Lane R, Tailler M, Nguyen TN, Ramm G, Lazarou M, De Nardo D, Kile BT, McArthur K. Exposure of the inner mitochondrial membrane triggers apoptotic mitophagy. Cell Death & Differentiation. 2024;31(3):10.1038/s41418-024-01260-2
Rao S, Skulsuppaisarn M, Strong LM, Ren X, Lazarou M, Hurley JH, Hummer G. Three-step docking by WIPI2, ATG16L1, and ATG3 delivers LC3 to the phagophore. Science Advances. 2024;10(6):10.1126/sciadv.adj8027
Gan ZY, Callegari S, Nguyen TN, Kirk NS, Leis A, Lazarou M, Dewson G, Komander D. Interaction of PINK1 with nucleotides and kinetin. Science Advances. 2024;10(3):10.1126/sciadv.adj7408
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