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Areas
  • Glycoproteins
  • Fundamental biology
  • Biologics
  • Proteases
  • Structural biology
Themes / Divisions

About

I am a highly qualified protein biochemist with a passion for exploring the intricate world of recombinant protein production and characterization. My academic background includes a Master’s degree in Biology from the University of Belgrade in Serbia and a PhD in Structural Biology from the Spanish National Cancer Research Centre.

Throughout my professional career, I have developed an extensive skill set in various areas of protein biochemistry, including structural biology, biochemical assay development, assay automation and miniaturization, and high-throughput screening. I have worked on numerous drug discovery and research projects in collaboration with both academic and industry partners, which has given me valuable insights into the drug discovery process.

Currently, I am leading a Protein Production Facility at WEHI, which specializes in producing high-quality recombinant proteins. Our facility uses state-of-the-art technologies and methodologies to produce proteins of the highest purity and quality. We work closely with researchers to optimize the protein production process to meet their specific research needs. Overall, my expertise in protein biochemistry, combined with my leadership of the PPF at WEHI, allows me to make significant contributions to drug discovery and other research initiatives, advancing scientific knowledge and ultimately improving human health.

Publications

Selected publications from Dr Marija Dramicanin

Dramicanin M, Lim K, Monard S. Fluorescent Protein Production, Purification, and Coupling to Microspheres. Current Protocols. 2023;3(4):10.1002/cpz1.745

Järvå MA, Dramicanin M, Lingford JP, Mao R, John A, Jarman KE, Grinter R, Goddard-Borger ED. Structural basis of substrate recognition and catalysis by fucosyltransferase 8. Journal of Biological Chemistry. 2020;295(19):10.1074/jbc.ra120.013291

McArthur K, Whitehead LW, Heddleston JM, Li L, Padman BS, Oorschot V, Geoghegan ND, Chappaz S, Davidson S, San Chin H, Lane RM, Dramicanin M, Saunders TL, Sugiana C, Lessene R, Osellame LD, Chew T-L, Dewson G, Lazarou M, Ramm G, Lessene G, Ryan MT, Rogers KL, van Delft MF, Kile BT. BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis. Science. 2018;359(6378):10.1126/science.aao6047

Dramićanin M, López-Méndez B, Boskovic J, Campos-Olivas R, Ramón-Maiques S. The N-terminal domain of MuB protein has striking structural similarity to DNA-binding domains and mediates MuB filament–filament interactions. Journal of Structural Biology. 2015;191(2):10.1016/j.jsb.2015.07.004

Dramićanin M, Ramón-Maiques S. MuB gives a new twist to target DNA selection. Mobile Genetic Elements. 2013;3(5):10.4161/mge.27515

Mizuno N, Dramićanin M, Mizuuchi M, Adam J, Wang Y, Han Y-W, Yang W, Steven AC, Mizuuchi K, Ramón-Maiques S. MuB is an AAA+ ATPase that forms helical filaments to control target selection for DNA transposition. Proceedings of the National Academy of Sciences of the United States of America. 2013;110(27):10.1073/pnas.1309499110

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