Gattu AK, Tanzer M, Yaron-Barir TM, Johnson JL, Jayavelu AK, Pan H, Dreyfuss JM, Cantley LC, Mann M, Kahn CR. Cell-intrinsic insulin signaling defects in human iPS cell–derived hepatocytes in type 2 diabetes. Journal of Clinical Investigation. 2025;135(8):10.1172/jci183513
M. Bader S, Calleja DJ, Devine SM, Kuchel NW, Lu BGC, Wu X, Birkinshaw RW, Bhandari R, Loi K, Volpe R, Khakham Y, Au AE, Blackmore TR, Mackiewicz L, Dayton M, Schaefer J, Scherer L, Stock AT, Cooney JP, Schoffer K, Maluenda A, Kleeman EA, Davidson KC, Allison CC, Ebert G, Chen G, Katneni K, Klemm TA, Nachbur U, Georgy SR, Czabotar PE, Hannan AJ, Putoczki TL, Tanzer M, Pellegrini M, Lechtenberg BC, Charman SA, Call MJ, Mitchell JP, Lowes KN, Lessene G, Doerflinger M, Komander D. A novel PLpro inhibitor improves outcomes in a pre-clinical model of long COVID. Nature Communications. 2025;16(1):10.1038/s41467-025-57905-4
Horne CR, Dite TA, Young SN, Mather LJ, Dagley LF, Johnson JL, Yaron-Barir TM, Huntsman EM, Daly LA, Byrne DP, Cadell AL, Ng BH, Yousef J, Multari DH, Shen L, McAloon LM, Manning G, Febbraio MA, Means AR, Cantley LC, Tanzer MC, Croucher DR, Eyers CE, Eyers PA, Scott JW, Murphy JM. PSKH1 kinase activity is differentially modulated via allosteric binding of Ca2+ sensor proteins. Proceedings of the National Academy of Sciences of the United States of America. 2025;122(8):10.1073/pnas.2420961122
Nordmann TM, Anderton H, Hasegawa A, Schweizer L, Zhang P, Stadler P-C, Sinha A, Metousis A, Rosenberger FA, Zwiebel M, Satoh TK, Anzengruber F, Strauss MT, Tanzer MC, Saito Y, Gong T, Thielert M, Kimura H, Silke N, Rodriguez EH, Restivo G, Nguyen HH, Gross A, Feldmeyer L, Joerg L, Levesque MP, Murray PJ, Ingen-Housz-Oro S, Mund A, Abe R, Silke J, Ji C, French LE, Mann M. Spatial proteomics identifies JAKi as treatment for a lethal skin disease. Nature. 2024;635(8040):10.1038/s41586-024-08061-0
Gattu A, Tanzer M, Yaron T, Cantley L, Kahn CR. 8569 Defining Cell-Intrinsic Defects In Hepatic Insulin Resistance In Type 2 Diabetes Using A Human iPS Cell-Derived Disease-In-A-Dish Model. Journal of the Endocrine Society. 2024;8(Supplement_1):10.1210/jendso/bvae163.723
Hoeft K, Koch L, Ziegler S, Zhang L, Luetke S, Tanzer MC, Mohanta D, Schumacher D, Schreibing F, Long Q, Kim H, Klinkhammer BM, Schikarski C, Maryam S, Baens M, Hermann J, Krieg S, Peisker F, De Laporte L, Schaefer GJL, Menzel S, Jankowski J, Humphreys BD, Wahida A, Schneider RK, Versele M, Boor P, Mann M, Sengle G, Hayat S, Kramann R. ADAMTS12 promotes fibrosis by restructuring extracellular matrix to enable activation of injury-responsive fibroblasts. Journal of Clinical Investigation. 2024;134(18):10.1172/jci170246
Tanzer MC. You are what you eat and how you digest it! A discussion on inflammatory efferocytosis. Frontiers in Cell and Developmental Biology. 2023;11:10.3389/fcell.2023.1132696
Tanzer MC, Tummers B, Poon IKH. Editorial: Cell death: from its induction to the removal of dying cells!. Frontiers in Cell and Developmental Biology. 2023;11:10.3389/fcell.2023.1195775
Stafford CA, Gassauer A-M, de Oliveira Mann CC, Tanzer MC, Fessler E, Wefers B, Nagl D, Kuut G, Sulek K, Vasilopoulou C, Schwojer SJ, Wiest A, Pfautsch MK, Wurst W, Yabal M, Fröhlich T, Mann M, Gisch N, Jae LT, Hornung V. Phosphorylation of muramyl peptides by NAGK is required for NOD2 activation. Nature. 2022;609(7927):10.1038/s41586-022-05125-x
Skowronek P, Thielert M, Voytik E, Tanzer MC, Hansen FM, Willems S, Karayel O, Brunner A-D, Meier F, Mann M. Rapid and In-Depth Coverage of the (Phospho-)Proteome With Deep Libraries and Optimal Window Design for dia-PASEF. Molecular & Cellular Proteomics. 2022;21(9):10.1016/j.mcpro.2022.100279
