Brain Cancer Research Lab

Laboratory Head
Laboratory Head
Laboratory Head
17 members

About the lab

Every five hours an Australian is diagnosed with brain cancer, a devastating illness that kills more children in Australia than any other disease and more people under 40 than any other cancer.

Currently, we lack effective treatments for many brain cancers, making this a terminal diagnosis for many patients. The major challenge is that resistance to treatment always occurs and is poorly understood.

In the Brain Cancer Research Laboratory, Dr Jim Whittle, Dr Saskia Freytag, and Dr Sarah Best are working to improve the diagnosis for brain cancer patients using advanced diagnostics, as well as developing new models to understand resistance, and investigating novel ways to treat brain cancer.

Our mission

Unravelling the complexities of adult glioma.


1) Characterisation of the heterogeneous glioma tumour microenvironment at single cell spatial resolution

Moffet et al., biorvix 2023: https://www.biorxiv.org/content/10.1101/2023.03.13.531204v1

2) Adaptation of new methods

Flow Cytometry protocol for all brain cell types

CNVkit for GeoMx data: https://www.biorxiv.org/content/10.1101/2023.03.13.531204v1

3) Establishment of multiple innovative clinical trials


Attendees at the Brain Cancer Research Laboratory scientific retreat
Above: The Brain Cancer Research Laboratory holds annual scientific retreats together with their consumer team and close scientific collaborators.

Lab research projects

Lab team

We are motivated to equip the next generation of scientists, bringing together biologists, clinicians and bioinformaticians to work on highly multi-disciplinary projects.

We collaborate extensively within The Brain Cancer Centre providing biological, clinical and bioinformatics support.

17 members
Dr Joseph Sia
Senior Clinical Research Officer
Dr Elizabeth Mason
Project Manager
Ehsan Ramezani
PhD Student
Lucy Riley
Clinical Coordinator
Jasmine Pignatelli
Research Assistant
Tianyao Lu
Research Assistant
PhD Student
Dr Jurgen Kriel
Senior Research Officer
Dr Adam Valkovic
Research Assistant
Research Assistant
Program Manager
Research Officer
Research Assistant
Interested in supporting our research?

Your support will help WEHI’s researchers make discoveries and find treatments to ensure healthier, longer lives for you and your loved ones.

Contact our friendly team to find out how you can help.