National Drug Discovery Centre

Our facilities are equipped with two ultra-high throughput robotic platforms for biochemical and cell-based assays. These configurable platforms can support incubation steps and multiple reagent additions, as well as readout options that include whole-plate fluorometric imaging, high-throughput flow cytometry, high-content imaging and multi-mode plate reader screens.

• High-throughput flow cytometry
• Whole-plate fluorometric imaging (FLIPR)
• Time-resolved fluorescence
• Fluorescence
• Fluorescence polarisation
• Luminescence
• FRET
• High-content imaging
• Absorbance

Applicants from Australian research institutes and small-to-medium enterprises may be eligible to apply for a screening subsidy, generously sponsored by the Australian Government and Therapeutic Innovation Australia.

This subsidy reduces the outlay for a standard screening campaign to a small fraction of the actual cost of running it. Subsidised screens will be awarded competitively through bi-annual selection rounds. Successful applications are chosen by an independent panel of drug discovery experts from around Australia.

The charges for a subsidised project vary but would typically be only around $45,000 to screen a library of 300,000 small molecules, provided that the assay can be miniaturised to 1536-well format by our staff.

Researchers who are ineligible to apply for subsidised screens are still encouraged to contact us regarding the possibility of collaborative or contract-based projects.