The COMET is a hyperplex spatial biology platform. Using an iterative cyclic imaging strategy, it allows the detection of up to 80 (protein) biomarkers in a single tissue section and a single protocol, preserving spatial context and tissue integrity.
The system uses standard unconjugated, off-the-shelf antibodies to deeply profile the tissue microenvironment, uncover cellular heterogeneity, and accelerate biomarker discovery.
In addition, the COMET allows for the simultaneous detection of up to 12 RNA targets in parallel with protein markers, enabling integrated spatial multi-omics analyses in the same sample.