Every living cell has a dynamic and continuously changing ‘cytoskeleton’ made up of microtubules and actin filaments that give the cell its shape, help organise its parts and provide a basis for movement and cell division.
Honours student Hanadi has used lattice light sheet microscopy to show the remarkable abilities of living cells to reorganise and change their form.
In each of the four ‘seasons’, Hanadi has used different fluorescent markers to tag microtubules, actin and a microtubule-associated protein called doublecortin-like kinase 1 (DCLK1).
DCLK1 is highly expressed in a range of cancers and may be involved in the ability of cancer cells to migrate and invade normal tissues, making it a potential target for the development of cancer treatments.
FIRST PLACE | MOVING IMAGE CATEGORY
Music by Nicholas Dullow