Adams G, Dans MG, Zhou Q, Su W, Ngo A, Jarman KE, Fawaz MV, Kelly MJ, McCauley JA, Olsen DB, Boddey JA, Cowman AF, Sleebs BE. Activity Refinement and Property Assessment of Peptidomimetics with Potent Antimalarial Activity That Target Plasmepsin V. ACS Infectious Diseases. 2026;12(9):10.1021/acsinfecdis.6c00314
Dans M, Awalt JK, Nguyen N, Palandri J, Ngo A, Jarman KE, Jeon JH, Yeo T, Park H, Uhlemann A-C, Mao EY, Gancheva MR, Wilson DW, Mukherjee P, Chakraborty A, Kristan M, Stewart L, Sutherland CJ, Baud D, Brand S, Fidock DA, Jackson PF, Cowman AF, Sleebs BE. 2‑Amino-3,4-Dihydroquinazolines Exhibit Potent Antimalarial Activity by Targeting Plasmepsin X. ACS Infectious Diseases. 2026;12(8):10.1021/acsinfecdis.6c00258
Farrell A, Dall G, Vandenberg CJ, Shield-Artin K, Kyran EL, Blackmore T, Lim R, Taylor R, Neagle C, Ratnayake G, Tan T, Mouradov D, Hadla A, Jarman K, Beard S, Jarratt A, Penington JS, Wakefield MJ, Papenfuss AT, Scott CL, Barker HE. High-throughput drug screening identifies EGFR/MAPK pathway targeting sensitivities in organoid models of ovarian carcinosarcoma. Journal of Experimental & Clinical Cancer Research. 2026;45(1):10.1186/s13046-025-03629-8
Mansouri M, Dans MG, Low Z, Loi K, Jarman KE, Penington JS, Qiu D, Lehane AM, Crespo B, Gamo F, Baud D, Brand S, Jackson PF, Cowman AF, Sleebs BE. Exploration and Characterization of the Antimalarial Activity of Pyrimidine‐2,4‐Diamines for which Resistance is Mediated by the ABCI3 Transporter. ChemMedChem. 2026;21(1):10.1002/cmdc.202500739
Su W, Nguyen W, Siddiqui G, Dziekan JM, Marapana D, Penington JS, Mehra S, Razook Z, McCann K, Ngo A, Jarman KE, Barry AE, Papenfuss AT, Gilson PR, Creek DJ, Cowman AF, Sleebs BE, Dans MG. Deconvolution of the On-Target Activity of Plasmepsin V Peptidomimetics in Plasmodium falciparum Parasites. ACS Infectious Diseases. 2025;11(12):10.1021/acsinfecdis.5c00742
Nguyen W, Boulet C, Dans MG, Loi K, Jarman KE, Barnes CBG, Yeo T, Sheth T, Mukherjee P, Chakraborty A, Famodimu MT, Delves MJ, Pollard H, Sutherland CJ, Coyle R, Sevilleno N, Boonyalai N, Lee MCS, Rabie T, Birkholtz L-M, Baud D, Brand S, Chowdury M, de Koning-Ward TF, Fidock DA, Gilson PR, Sleebs BE. Optimization and Characterization of the Antimalarial Activity of N‑Aryl Acetamides that are Susceptible to Mutations in ROM8 and CSC1. Journal of Medicinal Chemistry. 2025;68(15):10.1021/acs.jmedchem.5c01471
Hodder AN, Sleebs BE, Adams G, Rezazadeh S, Ngo A, Jarman K, Scally S, Czabotar P, Wang H, McCauley JA, Olsen DB, Cowman AF. Structure–activity analysis of imino‐pyrimidinone‐fused pyrrolidines aids the development of dual plasmepsin V and plasmepsin X inhibitors. The FEBS Journal. 2025;292(11):10.1111/febs.70038
Pan B, Mountford SJ, Kiso M, Anderson DE, Papadakis G, Jarman KE, Tilmanis DR, Maher B, Tran T, Shortt J, Yamayoshi S, Kawaoka Y, Thompson PE, Greenall SA, Warner N. Targeted protein degraders of SARS-CoV-2 Mpro are more active than enzymatic inhibition alone with activity against nirmatrelvir resistant virus. Communications Medicine. 2025;5(1):10.1038/s43856-025-00863-1
Awalt JK, Ooi ZK, Ashton TD, Mansouri M, Calic PPS, Zhou Q, Vasanthan S, Lee S, Loi K, Jarman KE, Penington JS, Qiu D, Zhang X, Lehane AM, Mao EY, Gancheva MR, Wilson DW, Giannangelo C, MacRaild CA, Creek DJ, Yeo T, Sheth T, Fidock DA, Churchyard A, Baum J, Famodimu MT, Delves MJ, Kristan M, Stewart L, Sutherland CJ, Coyle R, Jagoe H, Lee MCS, Chowdury M, de Koning-Ward TF, Baud D, Brand S, Jackson PF, Cowman AF, Dans MG, Sleebs BE. Optimization and Characterization of N‑Acetamide Indoles as Antimalarials That Target PfATP4. Journal of Medicinal Chemistry. 2025;68(8):10.1021/acs.jmedchem.5c00614
Ashton TD, Calic PPS, Dans MG, Ooi ZK, Zhou Q, Loi K, Jarman KE, Palandri J, Qiu D, Lehane AM, Maity B, De N, Famodimu MT, Delves MJ, Mao EY, Gancheva MR, Wilson DW, Chowdury M, de Koning‐Ward TF, Baud D, Brand S, Jackson PF, Cowman AF, Sleebs BE. Lactam Truncation Yields a Dihydroquinazolinone Scaffold with Potent Antimalarial Activity that Targets PfATP4. ChemMedChem. 2024;19(24):10.1002/cmdc.202400549
