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About

I am a medical oncologist with a special interest in colorectal cancer.

My research is aimed at understanding the features of colorectal cancer that predict how a patient will experience the disease, such as whether they will respond to therapy and whether they are at risk of recurrence following surgery.

I am also exploring whether a simple blood test could be used for the early detection of cancer, diagnosing tumours before they spread, when the chance of cure is high.

Publications

Selected publications from Prof Jeanne Tie

McLachlan S-A, Singh M, Hayes T, Lundy J, Wong ZW, Chong G, Saqib A, Steel S, Aghmesheh M, Begbie S, Roohullah A, Beale P, Ng W, Diakos C, Srivastav R, Rai S, Wong M, Karikios D, Barnett M, Lum C, Underhill C, Poursoltan P, Karki B, Karapetis C, Price T, Khattak A, Wuttke M, Karanth N, Jeffery M, Yelamanchili R, Batra A, Roitman D, Gotfrit J, Mussawar I, Kassam S, Goffin J, Rask S, Hubay S, Chen E, Samimi S, Martel S, Zurawska U, Wong R, Sideris L, Tang P, McGhie J, Arif S, Ahmed S, Michael J, Shim K, Babak S, Armstrong D, Burkes R, Kavan P. Circulating tumor DNA-guided adjuvant therapy in locally advanced colon cancer: the randomized phase 2/3 DYNAMIC-III trial. Nature Medicine. 2025;:10.1038/s41591-025-04030-w

Wonglhow J, Wong H-L, Michael M, Heriot A, Guerra G, Mitchell C, Tie J. Survival Outcomes and Prognostic Factors in Metastatic Unresectable Appendiceal Adenocarcinoma Treated with Palliative Systemic Chemotherapy: A 10-Year Retrospective Analysis from Australia. Cancers. 2025;17(20):10.3390/cancers17203297

Zaman FY, Orchard SG, Polekhina G, Gibbs P, Bernstein WB, Macrae F, Tie J, Millar J, Gately L, Rodríguez LM, van Londen GJ, Mar V, Hiscutt E, Adler N, Kent A, Ong WL, Haydon A, Warner E, Chan AT, Zalcberg J. Association of non-steroidal anti-inflammatory medications and aspirin with colorectal cancer incidence in older adults. Journal of the National Cancer Institute. 2025;117(9):10.1093/jnci/djaf145

Curtis SD, Panda S, Li A, Xu H, Bai Y, Ogihara I, O’Reilly E, Wang Y, Dobbyn L, Popoli M, Ptak J, Nehme N, Silliman N, Tie J, Gibbs P, Ho-Pham LT, Tran BNH, Tran TS, Nguyen TV, Irajizad E, Goggins M, Wolfgang CL, Wang T-L, Shih I-M, Fader A, Lennon AM, Hruban RH, Bettegowda C, Gilbert L, Kinzler KW, Papadopoulos N, Vogelstein B, Vogelstein JT, Douville C. Minimizing and quantifying uncertainty in AI-informed decisions: Applications in medicine. Proceedings of the National Academy of Sciences of the United States of America. 2025;122(34):10.1073/pnas.2424203122

Curtis SD, Liu T, Bai Y, Wang Y, Panda S, Li A, Xu H, O’Reilly E, Dobbyn L, Popoli M, Ptak J, Silliman N, Thoburn C, Tie J, Gibbs P, Ho-Pham LT, Tran BNH, Tran TS, Nguyen TV, Konig MF, Petri M, Rosen A, Mecoli CA, Shah AA, Mulder F, van Es N, Bettegowda C, Kinzler KW, Papadopoulos N, Vogelstein JT, Vogelstein B, Douville C, Klok FA, Beyer-Westendorf J, Jara-Palomares L, Ageno W, Peters MJL, Delluc A, Best M, Guman N, Otten H-M, Mulder F, van Es N. Fragmentation signatures in cancer patients resemble those of patients with vascular or autoimmune diseases. Proceedings of the National Academy of Sciences of the United States of America. 2025;122(34):10.1073/pnas.2426890122

Michael M, Wong R, Gill S, Strickland AH, Pavlakis N, Shapiro JD, Link E, Farrell M, Ngan SY, Tie J, Heriot AG, Goldstein D, Mitchell C, Roth S, Wilson K, Mui M, Ramsay RG, Segelov E. The Ave-Rec Trial: Phase II Trial of PDL1/PD1 Blockade with Avelumab after Chemoradiotherapy for Locally Advanced Resectable T3B-4/N1-2 Rectal Cancer.Clinical Cancer Research. 2025;31(16):10.1158/1078-0432.ccr-25-0705

Allan Z, Wang Y, Tie J, Tebbutt N, Clemons N, Papadolpoulos N, Kinzler K, Vogelstein B, Liu DSH. 091. MULTI-OMICS EVALUATION OF PERITONEAL FLUID IN GASTROESOPHAGEAL CANCER: RESULTS FROM INTERIM ANALYSIS. Diseases of the Esophagus. 2025;38(Supplement_1):10.1093/dote/doaf061.006

Desmond B, Alukaidey L, Allan Z, Cabalag C, Clemons NJ, Michael M, Tie J, Tebbutt N, Duong CP, Liu DS. Neoadjuvant intraperitoneal chemotherapy in high-risk and cytology positive gastric cancer: a systematic review. Surgical Oncology. 2025;61:10.1016/j.suronc.2025.102237

Glewis S, Michael M, Gurney H, Olver I, Zdenkowski N, Ackland S, Kukard C, Jayawardana M, Silva SSM, Alexander M, Tie J, Galettis P, Martin JH. Feasibility and population exposure of 5‐fluorouracil using therapeutic drug monitoring (PREDICT‐5FU): A multicentre clinical trial. British Journal of Clinical Pharmacology. 2025;91(7):10.1002/bcp.70006

Burge ME, Espinoza D, Sjoquist KM, Siu DH, Mercieca-Bebber R, Chantrill LA, Karapetis CS, Steer CB, Yip S, Cuff J, Winata S, Tie J, Thaker DA, Srivastav R, Abdi E, Strickland A, Segelov E, Francesconi A, Price T, Ladwa R, Joubert W, Tebbutt NC. AGITG MONARCC: A Randomized Phase 2 Study of Panitumumab Monotherapy and Panitumumab Plus 5-Fluorouracil as First-Line Therapy for Older Patients With RAS and BRAF Wild Type Metastatic Colorectal Cancer. A Study by the Australasian Gastro-Intestinal Trials Group (AGITG). Clinical Colorectal Cancer. 2025;24(2):10.1016/j.clcc.2024.11.003

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