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About

Ben leads the Genito-Urinary (GU) research program within the Gibbs Lab at WEHI. His team focuses on generating Real World Evidence (RWE) to change practice in GU cancers.

Ben is also a medical oncologist at Peter MacCallum Cancer Centre where he leads the GU medical oncology group and trials program. He is an Associate Professor at the University of Melbourne. Ben also chairs the Phase 1 Trials Group within Cancer Trials Australia and the Germ Cell Tumour group within ANZUP.

At WEHI, Ben leads multi-national registries in Prostate cancer, Urothelial cancer, Testis cancer and Kidney cancer. Data from these registries have been utilized to describe treatment patterns, identify clinical and tissue-based biomarkers and inform future research strategies. Ben has expanded the out-reach of these registries to Asia, with sites now contributing from Singapore and Korea. Ben is recognized globally for his leadership in RWE in GU cancers. Ben is also internationally recognized as an expert in testicular cancer, utilizing his RWE leadership to drive pragmatic clinical trials aimed at improving long term outcomes for testicular cancer survivors.

Ben also leads the early development of novel therapeutics in GU cancers. He is globally respected for his knowledge and expertise in early phase, first time in human clinical trials. His role within developmental therapeutics is essential in connecting scientists to clinicians and facilitating a bench to bedside and back to bench approach to cancer research.

Publications

Selected publications from A/Prof Ben Tran

Panian J, Zhong C, Choi S, BA RQ, Ferrier E, Saad E, Saliby RM, Malvar C, Pal S, Ebrahimi H, Tran B, Jude E, Lalani A-K, Suarez C, De Velasco G, Kanesvaran R, Zarbá M, Chehade REH, Choueiri TK, Heng D, McKay R. 35 Efficacy of treatments post-lenvatinib in patients with advanced renal cell carcinoma (aRCC). The Oncologist. 2024;29(Supplement_1):10.1093/oncolo/oyae181.036

Marx G, Chowdhury S, Krieger L, Hovey E, Shapiro J, Tran B, Tan TH, Ng S, Woo HH. A practical guide for the use of apalutamide for non‐metastatic castration‐resistant prostate cancer in Australia. Asia-Pacific Journal of Clinical Oncology. 2024;20(4):10.1111/ajco.14054

Dholaria H, Tran B. Time to diversify: germline exome sequencing for men with testicular germ cell tumour. Translational Andrology and Urology. 2024;:10.21037/tau-24-85

Kostos L, Tran B, Azad AA. Combination of PARP Inhibitors and Androgen Receptor Pathway Inhibitors in Metastatic Castration-Resistant Prostate Cancer. Drugs. 2024;:10.1007/s40265-024-02071-y

Conduit C, Lewin J, Hong W, Sim I, Ahmad G, Leonard M, O’Haire S, Moody M, Hutchinson AD, Lawrentschuk N, Thomas B, Dhillon HM, Tran B. Pseudoephedrine for ejaculatory dysfunction after retroperitoneal lymph node dissection in testicular cancer. BJU International. 2024;:10.1111/bju.16481

Pal SK, Tran B, Haanen JBAG, Hurwitz ME, Sacher A, Tannir NM, Budde LE, Harrison SJ, Klobuch S, Patel SS, Meza L, Dequeant M-L, Ma A, He QA, Williams LM, Keegan A, Gurary EB, Dar H, Karnik S, Guo C, Heath H, Yuen RR, Morrow PK, Agarwal N, Srour SA. CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma. Cancer Discovery. 2024;14(7):10.1158/2159-8290.cd-24-0102

Hitchen N, Shahnam A, Manoharan S, Topp M, Mileshkin L, Lim AM, Whittle JR, Luen SJ, Solomon B, Lackovic K, Desai J, Tran B. Trends in phase 1 oncology clinical trials across Australia; Analysis of ClinicalTrials.gov 2012–2022. Asia-Pacific Journal of Clinical Oncology. 2024;:10.1111/ajco.14100

Weickhardt A, Foroudi F, Lawrentschuk N, Xie J, Sidhom M, Pal A, Grimison P, Zhang A, Ng S, Tang C, Hovey E, Chen C, Hruby G, Guminski A, McJannett M, Conduit C, Tran B, Davis ID, Hayne D. Pembrolizumab with Chemoradiation as Treatment for Muscle-invasive Bladder Cancer: Analysis of Safety and Efficacy of the PCR-MIB Phase 2 Clinical Trial (ANZUP 1502). European Urology Oncology. 2024;7(3):10.1016/j.euo.2023.09.011

Wahlroos S, Teng C, Tran B, Voskoboynik M, Gan HK, Spencer A, Kudva A, Song M, Lynch K, Yu Z, Desai J, Lemech CR. Results of a first-in-human, dose-escalation phase 1 study of the ERK1/2 inhibitor ATG-017 in patients with advanced solid tumors.Journal of Clinical Oncology. 2024;42(16_suppl):10.1200/jco.2024.42.16_suppl.e15114

Panian J, Zhong C, Choi S, Quinn R, Ferrier E, Saad E, Saliby RM, Malvar C, Pal SK, Ebrahimi H, Tran B, Weickhardt AJ, Lalani A-KA, Suárez C, de Velasco G, Kanesvaran R, Zarba M, CHOUEIRI TK, Heng DYC, McKay RR. Efficacy of post-lenvatinib treatments in patients (pts) with advanced renal cell carcinoma (aRCC).Journal of Clinical Oncology. 2024;42(16_suppl):10.1200/jco.2024.42.16_suppl.4538

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