A/Prof Ben Tran, Senior Clinical Research Fellow

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Ben leads the Genito-Urinary (GU) research program within the Gibbs Lab at WEHI. His team focuses on generating Real World Evidence (RWE) to change practice in GU cancers.

Ben is also a medical oncologist at Peter MacCallum Cancer Centre where he leads the GU medical oncology group and trials program. He is an Associate Professor at the University of Melbourne. Ben also chairs the Phase 1 Trials Group within Cancer Trials Australia and the Germ Cell Tumour group within ANZUP.

At WEHI, Ben leads multi-national registries in Prostate cancer, Urothelial cancer, Testis cancer and Kidney cancer. Data from these registries have been utilized to describe treatment patterns, identify clinical and tissue-based biomarkers and inform future research strategies. Ben has expanded the out-reach of these registries to Asia, with sites now contributing from Singapore and Korea. Ben is recognized globally for his leadership in RWE in GU cancers. Ben is also internationally recognized as an expert in testicular cancer, utilizing his RWE leadership to drive pragmatic clinical trials aimed at improving long term outcomes for testicular cancer survivors.

Ben also leads the early development of novel therapeutics in GU cancers. He is globally respected for his knowledge and expertise in early phase, first time in human clinical trials. His role within developmental therapeutics is essential in connecting scientists to clinicians and facilitating a bench to bedside and back to bench approach to cancer research.

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Publications

Selected publications from A/Prof Ben Tran

Panian J, Zhong C, Choi SH, Ly K, Quinn R, Ferrier E, Saad E, Saliby RM, Malvar C, Pal S, Ebrahimi H, Tran B, Jude E, Lalani A-K, Suarez C, Velasco GD, Kanesvaran R, Zarba M, Liow E, El Hajj Chehade R, Choueiri TK, Heng DYC, McKay RR. Efficacy of Treatments After Lenvatinib in Patients with Advanced Renal Cell Carcinoma. European Urology Focus. 2024;:10.1016/j.euf.2024.11.011

Hitchen N, Shahnam A, Manoharan S, Topp M, Mileshkin L, Lim AM, Whittle JR, Luen SJ, Solomon B, Lackovic K, Desai J, Tran B. Trends in phase 1 oncology clinical trials across Australia; Analysis of ClinicalTrials.gov 2012–2022. Asia-Pacific Journal of Clinical Oncology. 2024;20(6):10.1111/ajco.14100

McKenzie J, Conduit C, Hing MNL, Zlatic K, Stokes K, Disney S, Khot A, Harrison SJ, Lewin J, Tran B. Chemomobilisation Using Gemcitabine-Oxaliplatin for Salvage High Dose Chemotherapy and Autologous Stem Cell Transplant in Advanced Testicular Germ Cell Cancer. Clinical Genitourinary Cancer. 2024;22(6):10.1016/j.clgc.2024.102234

Ngo P, Ahmadi N, Ferguson P, Conduit C, O’Haire S, Kuchel A, Pranavan G, Weickhardt A, Tran B, Grimison P. Characteristics and outcomes among patients with delayed orchidectomy for advanced germ cell tumours. BJU International. 2024;134(S2):10.1111/bju.16546

Bentick G, Balasubramanian A, Anton A, Azad A, Brown S, Goh JCH, Wong SSL, Parente P, Shapiro J, Liow ECH, Torres J, Smith A, Steer C, Warren M, Gibbs P, Tran B, Weickhardt AJ. 366P Clinicopathological predictors of favourable response to docetaxel in patients with metastatic castration-resistant prostate cancer. Annals of Oncology. 2024;35:10.1016/j.annonc.2024.10.385

Conduit C, Lewin J, Hong W, Sim I, Ahmad G, Leonard M, O’Haire S, Moody M, Hutchinson AD, Lawrentschuk N, Thomas B, Dhillon HM, Tran B. Pseudoephedrine for ejaculatory dysfunction after retroperitoneal lymph node dissection in testicular cancer. BJU International. 2024;134(5):10.1111/bju.16481

Liu J, Hiwase M, Woon DTS, Thomas B, Tran B, Lawrentschuk N. Primary retroperitoneal lymph node dissection in stage II testicular seminoma: a systematic review. BJU International. 2024;:10.1111/bju.16536

Tran B, Mizokami A, Wang S-S, Li Y, Takeuchi T, Bain P, Liu Y, Maeng CY, Singh A, Kishiwada N, Cheng MS, Gowindah R, Si J, Han H. Understanding Experiences and Needs of Patients With Prostate Cancer Across Asia-Pacific: A Cross-Sectional Mixed-Methods Study. JU Open Plus. 2024;2(9):10.1097/ju9.0000000000000191

Kim GY, Conduit C, O’Haire S, Chong CY, Baenziger O, Lewin J, Thomas B, Lawrentschuk N, Stockler MR, Olver I, Grimison P, Tran B. Association between low total serum testosterone and body mass index in Australian survivors of testicular cancer: a retrospective analysis. Basic and Clinical Andrology. 2024;34(1):10.1186/s12610-024-00230-5

Zhong YY, Anton A, Xie O, Tan N, O’Haire S, Maleki S, Inderjeeth A, Parente P, Spain L, Gibbs P, Tran B. Impact of Comorbidities and Drug Interactions in Patients With Metastatic Castration-Resistant Prostate Cancer Receiving Androgen Receptor Pathway Inhibitors. JCO Oncology Practice. 2024;20(9):10.1200/op.24.00036

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A/Prof Ben Tran

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