Geoff Lindeman-Publications

Geoff Lindeman-Publications

Selected publications

  1. Merino D, Whittle JR, Vaillant F, Serrano A, Gong J-N, Giner G, Maragno A-L, Chanrion M, Schneider E, Pal B, Li X, Dewson G, Gräsel J, Liu K, Lalaoui N, Segal D, Herold MJ, Huang D, Smyth GK, Geneste O, Lessene G, Visvader JE, Lindeman GJ. Synergistic action of the MCL-1 inhibitor S63845 with current therapies in preclinical models of triple negative and HER2-amplified breast cancer. Sci Transl Med. 2017 9(401). pii: eaam7049 PMID: 28768804
  2. Nolan E, Savas P, Policheni AN, Darcy PK, Vaillant F, Mintoff C, Mariam Mansour M, Pang J-MB, Fox SB,  kConFab, Perou CM, Visvader JE, Gray DHD, Loi S, Lindeman GJ. Combined immune checkpoint blockade as a therapeutic strategy for BRCA1-mutated breast cancer. Sci Transl Med. 2017 9(393). pii: eaal4922. PMID: 28592566
  3. Nolan E, Vaillant F, Branstetter DB, Pal B, Giner G, Whitehead L, Lok SW, Mann GB, kConFab, Rohrbach K, Huang LY, Soriano R, Smyth GK, Dougall WC, Visvader JE*, Lindeman GJ*. RANK ligand as a potential target for breast cancer prevention in BRCA1 mutation carriers. Nature Med. 2016 22(8), 933–939. PMID: 27322743 *Equal senior author.
  4. Rios AC, Fu NY, Lindeman GJ, Visvader JE. In situ identification of bipotent stem cells in the mammary gland. Nature. 2014 Feb 20;506(7488):322-7. PMID: 24463516.
  5. Vaillant F, Merino D, Lee L, Breslin K, Pal B, Ritchie ME, Smyth GK, Christie M, Phillipson LJ, Burns CJ, Mann GB, Visvader JE, Lindeman GJ. Targeting BCL-2 with the BH3 Mimetic ABT-199 in Estrogen Receptor-Positive Breast Cancer. Cancer Cell. 2013 Jul 8;24(1):120-9. PMID: 23845444
  6. Asselin-Labat ML, Vaillant F, Sheridan JM, Pal B, Wu D, Simpson ER, Yasuda H, Smyth GK, Martin TJ, Lindeman GJ, Visvader JE. Control of mammary stem cell function by steroid hormone signalling. Nature. 2010 Jun 10;465(7299):798-802. PMID: 20383121.
  7. Lim E, Vaillant F, Wu D, Forrest NC, Pal B, Hart AH, Asselin-Labat ML, Gyorki DE, Ward T, Partanen A, Feleppa F, Huschtscha LI, Thorne HJ, Fox SB, Yan M, French JD, Brown MA, Smyth GK, Visvader JE, Lindeman GJ. Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers. Nature Medicine. 2009 Aug;15(8):907-13. PMID: 19648928.
  8. Visvader JE, Lindeman GJ. Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nature Reviews Cancer. 2008 Oct;8(10):755-68. PMID: 18784658.
  9. Asselin-Labat ML, Sutherland KD, Barker H, Thomas R, Shackleton M, Forrest NC, Hartley L, Robb L, Grosveld FG, van der Wees J, Lindeman GJ, Visvader JE. Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation. Nature Cell Biology. 2007 Feb;9(2):201-U103. PMID: 17187062.
  10. Shackleton M, Vaillant F, Simpson KJ, Stingl J, Smyth GK, Asselin-Labat ML, Wu L, Lindeman GJ, Visvader JE. Generation of a functional mammary gland from a single stem cell. Nature. 2006 Jan 5;439(7072):84-8. PMID: 16397499.