Dr Holly Anderton is a senior postdoctoral researcher in the Inflammation Division. Her research focuses on how regulated cell death pathways shape inflammatory skin disease and tissue repair, with a particular interest in how epithelial and immune cells respond to barrier damage.
In this seminar, Holly will present new work challenging the traditional view of necroptosis as a purely lytic, pro-inflammatory form of cell death. Using multiple models of cutaneous injury, her work suggests that RIPK3–MLKL signalling can act as a tunable stress-adaptive pathway in keratinocytes, influencing calcium signalling, differentiation and the pace of epidermal repair.