If you would like to give to a specific research program or support the work of a particular researcher, contact our fundraising team today.
WEHI has research projects in cancer, immunology and infectious diseases, feeding into our robust discovery and development pipeline. We are committed to the translation of our discoveries into improvements in disease diagnosis, prevention and treatment.
| Project name | Theme | Stage | Modality |
|---|---|---|---|
| Hit-to-Lead | Cell therapy | ||
| Hit-to-Lead | Small molecule | ||
| Hit discovery | Small molecule | ||
| Target validation | Biologic | ||
| Lead Optimisation | Biologics | ||
| Hit discovery | Biologic | ||
| Hit discovery | RNA technology | ||
| Target Validation | Small molecule | ||
| Target validation | RNA technology | ||
| Proof of concept | Reagent | ||
| Lead optimisation | Small molecule | ||
| Hit discovery | Biologic | ||
| Pilot system | Diagnostic | ||
| β-prototype | Diagnostic | ||
| α-prototype | Diagnostic | ||
| Hit-to-Lead | Small molecule | ||
| Target validation | Small molecule | ||
| Target validation | Small molecule | ||
| Target validation | Small molecule | ||
| β-prototype | Device |
A DC subset with superior antigen-presenting capability, engineered with a proprietary CAR design for immunotherapy.
A novel small molecule targeting a key susceptibility in MYC driven cancers.
A first-in-class small molecule inhibitor for blood cancers including AML.
An optimised human biologic targeting EphA10 for aggressive solid cancers.
A new therapy for global prevention of hemolytic disease of the newborn
Developing a first-in-class, anti-NINJ1 therapy for cell death associated diseases.
Targeting inflammatory cytokine signalling in autoimmune disease
Degradation of c-Rel for treating chronic autoimmune inflammatory disease.
A novel lung macrophage-targeted LNP therapy for COPD and respiratory diseases.
A media cocktail and culture system for in vitro human haematopoiesis.
Oral therapeutic targeting coronavirus Mpro; potential to minimise progression to severe disease and post-acute sequelae of COVID-19 (PASC / Long COVID).
Human antibodies targeting specifc bacterial glycans to treat antibiotic resistant gram negative bacterial infections.
Rapid and accurate TSAT testing for diagnosis and treatment of iron deficiency.
A high throughput diagnostic for relapsing liver malaria.
A high-throughput laboratory-based diagnostic for detecting hidden or cryptic liver stage Plasmodium vivax infections.
Using an epigenetic approach to turn on genes, the absence of which causes Prader Willi Syndrome, a devistating neurodevelopment disorder
A small molecule inhibitor of Bax-mediated apoptosis in dopaminergic neurons to prevent and treat Parkinson’s Disease.
Developing a small molecule activator of Pink1 for treatment of Parkinson’s Disease.
An effective and affordable plunge freezing device for cryogenic electron microscopy.