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- Alistair Brown
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- Diseases
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- A multi-pronged approach to targeting myeloproliferative neoplasms
- A new paradigm of machine learning-based structural variant detection
- A whole lot of junk or a treasure trove of discovery?
- Advanced imaging interrogation of pathogen induced NETosis
- Analysing the metabolic interactions in brain cancer
- Atopic dermatitis causes and treatments
- Boosting the efficacy of immunotherapy in lung cancer
- Building a cell history recorder using synthetic biology for longitudinal patient monitoring
- Characterisation of malaria parasite proteins exported into infected liver cells
- Deciphering the heterogeneity of the tissue microenvironment by multiplexed 3D imaging
- Defining the mechanisms of thymic involution and regeneration
- Delineating the molecular and cellular origins of liver cancer to identify therapeutic targets
- Developing computational methods for spatial transcriptomics data
- Developing drugs to block malaria transmission
- Developing models for prevention of hereditary ovarian cancer
- Developing statistical frameworks for analysing next generation sequencing data
- Development and mechanism of action of novel antimalarials
- Development of novel RNA sequencing protocols for gene expression analysis
- Discoveries in red blood cell production and function
- Discovering epigenetic silencing mechanisms in female stem cells
- Discovery and targeting of novel regulators of transcription
- Dissecting host cell invasion by the diarrhoeal pathogen Cryptosporidium
- Dissecting mechanisms of cytokine signalling
- Doublecortin-like kinases, drug targets in cancer and neurological disorders
- Epigenetic biomarkers of tuberculosis infection
- Epigenetics – genome wide multiplexed single-cell CUT&Tag assay development
- Exploiting cell death pathways in regulatory T cells for cancer immunotherapy
- Exploiting the cell death pathway to fight Schistosomiasis
- Finding treatments for chromatin disorders of intellectual disability
- Functional epigenomics in human B cells
- How do nutrition interventions and interruption of malaria infection influence development of immunity in sub-Saharan African children?
- Human lung protective immunity to tuberculosis
- Improving therapy in glioblastoma multiforme by activating complimentary programmed cell death pathways
- Innovating novel diagnostic tools for infectious disease control
- Integrative analysis of single cell RNAseq and ATAC-seq data
- Interaction with Toxoplasma parasites and the brain
- Interactions between tumour cells and their microenvironment in non-small cell lung cancer
- Investigation of a novel cell death protein
- Malaria: going bananas for sex
- Mapping spatial variation in gene and transcript expression across tissues
- Mechanisms of Wnt secretion and transport
- Multi-modal computational investigation of single-cell communication in metastatic cancer
- Nanoparticle delivery of antibody mRNA into cells to treat liver diseases
- Naturally acquired immune response to malaria parasites
- Organoid-based discovery of new drug combinations for bowel cancer
- Organoid-based precision medicine approaches for oral cancer
- Removal of tissue contaminations from RNA-seq data
- Reversing antimalarial resistance in human malaria parasites
- Role of glycosylation in malaria parasite infection of liver cells, red blood cells and mosquitoes
- Screening for novel genetic causes of primary immunodeficiency
- Single-cell ATAC CRISPR screening – Illuminate chromatin accessibility changes in genome wide CRISPR screens
- Spatial single-cell CRISPR screening – All in one screen: Where? Who? What?
- Statistical analysis of single-cell multi-omics data
- Structural and functional analysis of epigenetic multi-protein complexes in genome regulation
- Structural basing for Wnt acylation
- Structure, dynamics and impact of extra-chromosomal DNA in cancer
- Targeted deletion of disease-causing T cells
- Targeting cell death pathways in tissue Tregs to treat inflammatory diseases
- The cellular and molecular calculation of life and death in lymphocyte regulation
- The role of hypoxia in cell death and inflammation
- The role of ribosylation in co-ordinating cell death and inflammation
- Understanding Plasmodium falciparum invasion of red blood cells
- Understanding cellular-cross talk within a tumour microenvironment
- Understanding the genetics of neutrophil maturation
- Understanding the roles of E3 ubiquitin ligases in health and disease
- Unveiling the heterogeneity of small cell lung cancer
- Using combination immunotherapy to tackle heterogeneous brain tumours
- Using intravital microscopy for immunotherapy against brain tumours
- Using nanobodies to understand malaria invasion and transmission
- Using structural biology to understand programmed cell death
- Validation and application of serological markers of previous exposure to malaria
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Royalties distribution

WEHI distributes royalty payments to people who contribute to the commercialisation of our research.
Translating basic research into effective new drugs requires great entrepreneurship as well as great science. Our royalty distribution process recognises this work and rewards those whose efforts have led to positive commercial outcomes.
Eligible projects
We are currently seeking people who believe they contributed to the commercialisation of the following projects:
ConologsScope: Development of ultra-fast acting insulins based on cone snail insulin principles Contribution date: From 2016 (ongoing) Deadline for eligibility: Ongoing |
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RINCHScope: This project aims to develop a chimaeric antigen receptor (CAR) that, in addition to the regular biological activity of CARs, can also activate the JAK/STAT pathway and induce the accumulation of phosphorylated STAT3. Contribution date: From 2019 (ongoing) Deadline for eligibility: Ongoing |
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VenetoclaxScope: Including:
Contribution date: From 1988 to 14 June 2017 Deadline for eligibility: 14 June 2017 |
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MLKLScope: Investigations of the biology of MLKL and associated proteins in the regulation of necroptosis. Contribution date: From 2013 (ongoing) Deadline for eligibility: Ongoing |
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CISScope: Research aimed at identifying novel small molecules of CIS and exploring potential uses of CIS inhibitors in a range of normal and disease processes. This project has been expanded to include target validation and structural characterisation for SOCS family proteins, SOCS1 and SOCS2. Contribution date: From 2015 (ongoing) Deadline for eligibility: Ongoing |
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Capillary ColumnScope: Capillary column with integrated electrospray emitter and method of manufacture. Contribution date: From 2015 (ongoing) Deadline for eligibility: Ongoing |
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CIS NK cell therapyScope: Licensing of patent for deletion of Cish (CIS gene) in CAR-NK cells to enhance NK cell-based therapy for cancer. Contribution date: From 2015 (ongoing) Deadline for eligibility: Ongoing |
Other projects may be added to this list in the future. Please check this page on a regular basis to see if new projects are added.
What classifies as a contribution?
We recognise a contributor as a person who, while employed at the Institute for the primary purpose of research:
- Published a paper relevant to the commercialised project
- Was listed on a relevant patent
- Contributed to relevant commercial negotiations
- Contributed to a relevant clinical trial
The Institute has detailed eligibility criteria, which you can request by contacting the Business Development Office on the contacts below.
Contact us
If you believe you may be a contributor to a project listed above, please contact WEHI:
- Phone: +61 3 9345 2555
- Email: royalties@wehi.edu.au
Note: you will be required to provide evidence to substantiate your claim.
Privacy
Personal information gathered in the course of this process is handled in line with WEHI’s Privacy Policy.