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Areas
Diseases
  • Autoinflammatory disease
  • Neurodevelopmental disorder
Technologies
  • Molecular biology
  • Mouse genetics
  • Transcriptomics
  • CRISPR
Sections on this page

Publications

Selected publications from Dr Jacki Heraud-Farlow

Heraud-Farlow JE, Taylor SR, Chalk AM, Escudero A, Hu S-B, Goradia A, Sun T, Li Q, Nikolic I, Li JB, Fidalgo M, Guallar D, Simpson KJ, Walkley CR. GGNBP2 regulates MDA5 sensing triggered by self double-stranded RNA following loss of ADAR1 editing. Science Immunology. 2024;9(101):10.1126/sciimmunol.adk0412

Liang Z, Walkley CR, Heraud-Farlow JE. A-to-I RNA editing and hematopoiesis. Experimental Hematology. 2024;139:10.1016/j.exphem.2024.104621

Hu S-B, Heraud-Farlow J, Sun T, Liang Z, Goradia A, Taylor S, Walkley CR, Li JB. ADAR1p150 prevents MDA5 and PKR activation via distinct mechanisms to avert fatal autoinflammation. Molecular Cell. 2023;83(21):10.1016/j.molcel.2023.09.018

Liang Z, Goradia A, Walkley CR, Heraud-Farlow JE. Generation of a new Adar1p150−/− mouse demonstrates isoform-specific roles in embryonic development and adult homeostasis. RNA. 2023;29(9):10.1261/rna.079509.122

Liang Z, Chalk AM, Taylor S, Goradia A, Heraud‐Farlow JE, Walkley CR. The phenotype of the most common human ADAR1p150 Zα mutation P193A in mice is partially penetrant. EMBO Reports. 2023;24(5):10.15252/embr.202255835

Ruiz SM, Chalk AM, Goradia A, Heraud-Farlow J, Walkley CR. Over-expression of ADAR1 in mice does not initiate or accelerate cancer formation in vivo. NAR Cancer. 2023;5(2):10.1093/narcan/zcad023

Chalk AM, Taylor S, Heraud-Farlow JE, Walkley CR. The majority of A-to-I RNA editing is not required for mammalian homeostasis. Genome Biology. 2019;20(1):10.1186/s13059-019-1873-2

Heraud-Farlow JE, Chalk AM, Walkley CR. Defining the functions of adenosine-to-inosine RNA editing through hematology.Current Opinion in Hematology. 2019;26(4):10.1097/moh.0000000000000514

Heraud-Farlow JE, Chalk AM, Linder SE, Li Q, Taylor S, White JM, Pang L, Liddicoat BJ, Gupte A, Li JB, Walkley CR. Protein recoding by ADAR1-mediated RNA editing is not essential for normal development and homeostasis. Genome Biology. 2017;18(1):10.1186/s13059-017-1301-4

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