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- A new regulator of stemness to create dendritic cell factories for immunotherapy
- Advanced methods for genomic rearrangement detection
- Control of cytokine signaling by SOCS1
- Defining the protein modifications associated with respiratory disease
- Delineating the pathways driving cancer development and therapy resistance
- Developing a new drug that targets plasmacytoid dendritic cells for the treatment of lupus
- Development and mechanism of action of novel antimalarials
- Development of a novel particle-based malaria vaccine
- Development of tau-specific therapeutic and diagnostic antibodies
- Discovering novel therapies for major human pathogens
- Dissecting host cell invasion by the diarrhoeal pathogen Cryptosporidium
- Epigenetic biomarkers of tuberculosis infection
- Essential role of glycobiology in malaria parasites
- Evolution of haematopoiesis in vertebrates
- Human lung protective immunity to tuberculosis
- Identifying novel treatment options for ovarian carcinosarcoma
- Interaction with Toxoplasma parasites and the brain
- Interactions between tumour cells and their microenvironment in non-small cell lung cancer
- Investigating the role of mutant p53 in cancer
- Microbiome strain-level analysis using long read sequencing
- Minimising rheumatic adverse events of checkpoint inhibitor cancer therapy
- Modelling spatial and demographic heterogeneity of malaria transmission risk
- Naturally acquired immune response to malaria parasites
- Predicting the effect of non-coding structural variants in cancer
- Structural basis of catenin-independent Wnt signalling
- Structure and biology of proteins essential for Toxoplasma parasite invasion
- T lymphocytes: how memories are made
- TICKER: A cell history recorder for longitudinal patient monitoring
- Targeting host pathways to develop new broad-spectrum antiviral drugs
- Targeting post-translational modifications to disrupting the function of secreted proteins
- Targeting the epigenome to rewire pro-allergic T cells
- Targeting the immune microenvironment to treat KRAS-mutant adenocarcinoma
- The E3 ubiquitin ligase Parkin and mitophagy in Parkinson’s disease
- The molecular controls on dendritic cell development
- Understanding malaria infection dynamics
- Understanding the genetics of neutrophil maturation
- Understanding the neuroimmune regulation of innate immunity
- Understanding the proteins that regulate programmed cell death at the molecular level
- Using cutting-edge single cell tools to understand the origins of cancer
- When healthy cells turn bad: how immune responses can transition to lymphoma
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- Taking a single cell focus with the DROP-seq
- WEHI.TV
WHO Collaborating Centre for Anaemia Detection and Control
Researcher:
WHO Collaborating Centre for Anaemia Detection and Control
WEHI has been designated as the World Health Organization (WHO) Collaborating Centre for Anaemia Detection and Control.
Our anaemia researchers will support the WHO on the best approaches to diagnose and treat anaemia, including preventing iron deficiency.
A global problem
is leading studies into the use of iron supplements to
prevent anaemia in mothers and children.
Two billion people worldwide – including around a million Australians – are anaemic, meaning they have abnormally low levels of oxygen-carrying red blood cells or haemoglobin in their blood. Anaemia is especially prevalent in low-income countries.
Anaemia can have serious short- and long-term health consequences. These include fatigue, heart problems and susceptibility to certain infections such as malaria. Anaemia in pregnant women or young children can increase their susceptibility to pregnancy-associated complications, and can cause long-term developmental problems for the child.
Iron deficiency is the main cause of anaemia, but both conditions can be caused by a range of other health issues including cancer, inflammatory conditions and coeliac disease. Reducing the prevalence of iron deficiency is critical for many of the WHO’s Global Targets 2025, particularly around improving women’s and children’s health.
Improving health by combatting anaemia
The WHO Collaborating Centre for Anaemia Detection and Control enlists WEHI researchers into the WHO’s efforts to reduce anaemia. Our researchers provide the most up-to-date, evidence-based advice to WHO, to ensure global programs to combat anaemia are effective and relevant to the unique circumstances of different countries.
The WHO Collaborating Centre for Anaemia Detection and Control is led by Associate Professor Sant-Rayn Pasricha, a clinician-scientist and haematologist.
Associate Professor Pasricha leads international trials of iron interventions as a treatment for iron-deficiency anaemia in low-income countries. His laboratory also investigates how iron levels are controlled at the molecular level.
Super Content:
Institute researchers have launched one of the largest international efforts to prevent and treat maternal anaemia in developing countries.
The study will also investigate the impacts of iron deficiency on the developing infant brain.