Inflammation and Type 2 Diabetes

Inflammation and Type 2 Diabetes

Part 1 of two animations about type 2 diabetes.

This animation describes the process of inflammation in type 2 diabetes via a unique structure called the inflammasome. Over time, this process damages the pancreas, eventually leading to decreased insulin secretion and inability to control blood glucose levels. Chronic inflammatory 'lifestyle diseases' such as T2D are rapidly increasing in the western world and will pose a huge health burden in future.

Maja Divjak, 2014

Topics - Master

Immune system, Diabetes

Request a download

Submitted by admin on Tue, 12/09/2017 - 10:34am

I have read the Terms of Use.

View Content: 
Beta insulin release
Insulin Production and Type 1 Diabetes

How insulin is normally produced in the body and how its production is destroyed in type 1...

Chromosome DNA coil
DNA Central Dogma Part 1 - Transcription

Various DNA molecular visualizations derived from x-ray crystallography and other data sets, and...

Herpes animation still
Virus One Billion Times

Molecular structures built to scale at one billion times magnification, using the raw scientific...

Visualisation of mitochondria interior
Synthesis of ATP (Respiration series)

This animation shows how the proton gradient across the mitochondrial membrane powers the ATP...

Growing breast stem cells
Breast Stem Cells

An overview of the human mammary gland with a focus on the role of breast stem cells during...

Malaria parasite in the bloodstream
Malaria Lifecycle Part 2: Mosquito Host

The complete malaria lifecycle, derived from scientific data sets, microscopy and published...

X inactivation process
X Inactivation and Epigenetics

X inactivation is a vital process that occurs in all DNA-containing cells of the female body. It...

Haem blood cells
Haemoglobin and Sickle Cell Anaemia

DNA molecular visualizations derived from x-ray crystallography and other data sets, and imbued...

Central dogma
Molecular Visualisations of DNA

The dynamics and molecular shapes were based on X-ray crystallographic models and other published...

Liver infected with malaria
Malaria Lifecycle Part 1: Human Host

Infection of a human child via mosquito bite, through invasion of cellular tissues including the...

Breast cancer animation still image
Origin of Breast Cancer

This animation visualises research published in Nature Medicine (Vol 15, Issue 8, 2009) by the...

Clonal selection
The Immune System

'Fighting Infection by Clonal Selection' was created to commemorate the 50th anniversary of...

Apoptosis
Apoptosis and Signal Transduction

Exploring the Fas signal transduction pathway that induces apoptosis.

CSF stem cell colony
Colony Stimulating Factor (CSF)

Colony Stimulating Factors (CSF) stimulate stem cells in bone marrow to form specialised white...

Visualisation of the pyruvate molecule
Pyruvate Dehydrogenase Complex (Respiration series)

This animation connects glycolysis with the citric acid cycle and the electron transport chain in...

Visualisation of the electron transport chain
Respiration: teacher resources

Created in collaboration with HHMI BioInteractive.org this collection of free biomolecular...

Animation still of RNA transcription activation
Sunshine Vitamin

Vitamin D from the sun’s rays can switch on all kinds of important processes in your body.

DNA replication
DNA Central Dogma Part 2 - Translation

Visualizations derived from x-ray crystallography and other data sets, and imbued with dynamic...

Visualisation of the citric acid cycle
Citric Acid Cycle (Respiration series)

This animation presents the enzyme reactions of the citric acid cycle, central to cellular...

DNA
Restriction Enzyme EcoR1

Various DNA molecular visualizations derived from x-ray crystallography and other data sets.

Dynein and Kinesin
Chromosome and Kinetochore

A multi-scale reconstruction of the organisation and structural features of DNA inside a...

Still image from biomedical animation showing protein p53
p53 Tumour Suppressor

The protein p53 plays a central role in determining whether a damaged cell lives or dies.

Still image from Apoptosis and venentoclax animation
Apoptosis and venetoclax

Programmed cell death, and how the drug venetoclax works with this process to treat cancer.

Insulin receptor animation still
Insulin Receptor and Type 2 Diabetes

The role of the insulin receptor in type 2 diabetes.

Mendel animation
Mendel: The Legacy

This state-of-the-art visual and orchestral spectacular in Brno, Czech Republic, celebrates 150...

Screenshot from animation
Cytotoxic T cells

The animation by Etsuko Uno illustrates how cytotoxic T cells kill virus-infected cells.

Visualisation of glycolysis
Glycolysis (Respiration series)

The glucose molecule is the energy source that provides power for your cells.

Central dogma
Body Code

A selection of biomedical animations that explore the human body at the microscopic and molecular...

Breast stem cells
Control of Breast Stem Cells

How breast stem cells respond to steroid hormone despite the cells not having any steroid...

Ubiquitin and Parkinson’s Disease animation still image
Ubiquitin and Parkinson’s Disease

This animation illustrates the role of ubiquitin in controlling the fate and activity of other...

Visualisation of the molecule ATP
ATP (Respiration series)

In this WEHI.TV animation we see two examples of how ATP provides energy for molecular activity...

Visualisation of the electron transport chain
Electron Transport Chain (Respiration series)

This animation visualises the molecular mechanisms of the electron transport chain.