Sonia Gandhi is a Principal Group Leader of the Neurodegeneration Biology Laboratory, and a Deputy Research Director, at The Francis Crick Institute. Her research program focusses on understanding the molecular and cellular mechanisms that cause neurodegenerative diseases, specifically familial and sporadic forms of Parkinson’s disease. She is a Professor of Neurology at UCL, where she leads a translational research centre, the UCL Queen Square Movement Disorders Centre, which brings together healthcare professionals and researchers to develop precision medicine approaches for patients with Parkinson’s.
Her laboratory adopts an interdisciplinary approach combining physical chemistry, stem cell biology, single cell, spatial and computational neuroscience to study protein misfolding in human systems, and the functional consequences of aggregation. Her laboratory builds patient-derived stem cell models of the brain to advance target identification, drug development for disease modifying therapies, and predictive approaches for personalised medicine. As a clinician scientist, Sonia leads a clinical research centre for Parkinson’s to accelerate the translation from scientific discovery to improvements in clinical care.