Richard Drake is a Professor in the Department of Pharmacology and Immunology at the Medical University of South Carolina in Charleston, and SmartState Endowed Chair in Proteomics. He is Director of the MUSC Proteomics Center and part of the Bruker-MUSC Center of Excellence in Clinical Glycomics. His lab developed the workflows for glycan-targeted mass spectrometry imaging of clinical tissues and biofluids for biomarker discovery and development of new diagnostics. Current efforts are in the large scale application of N-glycan MS imaging methods to identify glycan biomarker panels associated with tumor, stroma and immune regions of cancer and auto-immune disease tissues. The glycan imaging workflows are highly synergistic with emerging multi-modality spatial-omic analysis strategies at the macro and single cell levels, with emphasis on the characterization of immune cell glycosylation.