WEHI Parkinson’s Disease Special Seminar hosted by Professor Grant Dewson

Professor Kalle Gehring

Professor of Biochemistry, School of Biomedical Sciences – McGill University, Canada

Activation of the Ubiquitin Ligase Parkin by a Molecular Glue

Davis Auditorium

Join via TEAMS

Including Q&A session 

Professor Kalle Gehring trained at the University of California at Berkeley (PhD, Microbiology) and, as a postdoctoral fellow at the Ecole Polytechnique in France where he discovered a cytosine-based four-stranded DNA structure. At McGill University in Montreal, Canada, his research group works on parkin, a ubiquitin ligase that protects against Parkinson’s disease. Recent studies discovered a class of small molecules that activate parkin without phosphorylation by acting as molecular glues. The compounds provide the basis for the design of first therapeutics to slow disease progression by enhancing parkin activity. The Gehring laboratory also works on a recently discovered signalling pathway involving cysteine phosphorylation and has been active leading grants for equipment and training in structural biology and biophysics.

Lab website: www.gehringlab.net

All welcome!