Professor Emma Hamilton-Williams’ career focuses on understanding how immune tolerance is disrupted leading to the development of the autoimmune type 1 diabetes. She received her PhD from the Australian National University, followed by postdoctoral training in Germany and the Scripps Research Institute in the USA. In 2012, she started a laboratory at the Frazer Institute, University of Queensland where she aims to find new ways to prevent or treat the underlying immune dysfunction causing autoimmunity. She has received near continual funding from Breakthrough T1D (formally JDRF) and NHMRC across her career.
Hamilton-Williams is Chief Scientific Officer for the Australia-wide ‘ENDIA’ pregnancy-birth cohort study of children at increased risk of type 1 diabetes, which aims to uncover the environmental drivers of this disease. Her laboratory uses big-data approaches including proteomics, metabolomics and metagenomics as well as human-to-mouse microbiome transplant studies to understand the function of the gut microbiota in type 1 diabetes. She recently conducted a clinical trial of a microbiome-targeting biotherapy aimed at restoring a healthy microbiome and immune tolerance, with an ultimate aim of preventing type 1 diabetes.