WEHI Postgraduate Seminar Series hosted by the Education Committee
 

Professor Andreas Strasser
Division Head, Blood Cells and Blood Cancer division, WEHI
 

Discovery of tumour suppression

Davis Auditorium

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Including Q&A session

Cancer is caused by mutations in the genome. Conceptually, the development of a cancer can be driven by mutations in genes that cause abnormally increased activation of a process; these genes are called proto-oncogenes or oncogenes, including c-MYC, RAS or BCR-ABL. However, neoplastic transformation can be prevented in cells by so-called tumour suppressors, including p53 and RB. I will describe how the concept of tumour suppression was discovered and describe some of the research that led to the discovery of tumour suppressor genes and their functions.

All welcome!