WEHI Blood Cells and Blood Cancer Special Seminar hosted by Professor Gemma Kelly

Matthew Witkowski, PhD

Assistant Professor – Department of Pediatrics, University of Colorado Anschutz Medical Campus, USA

Inhibiting Free Fatty Acid Transport to Improve CAR-T Cell Therapy of Relapsed B-Cell Acute Lymphoblastic Leukemia

 

Davis Auditorium

Join via TEAMS

Including Q&A session

During his PhD at the Walter and Eliza Hall Institute with Dr. Ross Dickins, Matt Witkowski developed novel mouse models to investigate how tumor-suppressor IKAROS regulates transcriptional programs in T-cell Acute Lymphoblastic Leukemia (T-ALL) and BCR1::ABL+ B-ALL. During his postdoctoral training at NYU School of Medicine with Dr. Iannis Aifantis, he investigated the bone marrow microenvironment in B-ALL, identifying leukemia-associated non-classical monocytes as a targetable component that can enhance therapeutic responses. Matt  is currently an Assistant Professor at the University of Colorado Anschutz Medical Campus whose research focuses on overcoming treatment resistance in high-risk B-cell acute lymphoblastic leukemia (B-ALL). His team aims to identify critical genetic and metabolic determinants driving B-ALL resistance to chemotherapy and chimeric antigen receptor-T cell therapy.

All welcome!