Dr Quentin Gouil – Epigenetics & Development division

21/06/2023 1:00 pm - 21/06/2023 2:00 pm
Davis Auditorium

WEHI Wednesday Seminar hosted by Professor Matt Ritchie

Dr Quentin Gouil
Senior Research Officer – Ritchie Laboratory, Epigenetics & Development division – Healthy Development & Ageing Theme, WEHI

Full-length genomics with nanopore sequencing


Davis Auditorium

Join via SLIDO enter code #WEHIWEDNESDAY

Including Q&A session


Long-read sequencing is transforming genomics, enabling the comprehensive and scalable sequencing of native nucleic acids. The recent completion of the human genome in 2022, two decades after its initial draft assembly, marked the coming-of-age of the technology and led to long-read sequencing being declared “Method of the Year 2022” by Nature Methods. I will show how we have harnessed the power of nanopore sequencing at WEHI to address diverse scientific challenges, focusing on three applications: full-length characterisation of antibody transcripts, plasmid validation and bacterial epigenetics, and allele-resolved mammalian epigenetics. This research benefits our routine practice of science, opens up avenues for basic science, and holds potential for improved diagnostics of human disease.


As an NHMRC Emerging Leader Investigator in the Ritchie lab, I use cutting-edge genomic and computational methods to unravel the complexities of epigenetic regulation in health and disease. I am an expert on long-read sequencing technologies, collaborating broadly to achieve complete characterisations of transcriptomes, genomes and epigenomes in multiple organisms. My main areas of focus are genomic imprinting, X inactivation and repeat silencing.


All welcome!

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