ASI Visiting Speaker Program hosted by Dr Lucille Rankin

Dr Matthew Hepworth

Sir Henry Dale Fellow, Lydia Becker Institute of Immunology and Inflammation, University of Manchester, UK

ILC regulatory networks in mucosal barrier tissue microenvironments

 

Davis Auditorium

Join via ZOOM 

Including Q&A session

Innate Lymphoid Cells are tissue-resident effector lymphocytes with broad and complex roles in maintaining tissue homeostasis, mediating immunity and driving inflammatory pathology. Contextual cues present within the local tissue microenvironment act to modulate ILC function and facilitate cellular crosstalk, with disruption of these homeostatic circuits leading to disease. This talk will explore emerging mechanisms of ILC regulation within barrier tissues across a range of biological systems.

Matt Hepworth is a mucosal immunologist at the University of Manchester, UK. His postdoctoral work in Greg

Sonnenberg’s lab at UPenn, Philadelphia (and later Weill Cornell Medicine, New York City) identified a novel role forILCs in regulating the adaptive immune response in intestinal inflammation and Inflammatory Bowel Disease. In 2016, he returned to the University of Manchester as a Wellcome Trust fellow where he leads his own research group investigating how Innate Lymphoid Cells (ILCs) interact with the immune system, diet, and microbiota to maintain tissue homeostasis.

All Welcome!