WEHI Wednesday Seminar hosted by Professor Kelly Rogers
 

Dr Maria Tanzer

Laboratory Head

Advanced Technology & Biology and Inflammation divisions

New Medicines & Advanced Technologies and Infection, Inflammation & Immunity Themes, WEHI

Resolving inflammation with the power of proteomics

 

Davis Auditorium

Join via SLIDO enter code #WEHIWednesday

Including Q&A session
 

Chronic inflammation arises from dysregulated inflammatory signalling and inefficient resolution processes. Macrophages play a critical role in both inflammation and its resolution. Macrophages drive inflammatory signalling by sensing damage- and pathogen-associated molecular patterns and promote wound healing by removing dead cells. I will present our approach to employ cutting-edge proteomics, including phosphoproteomics, secretomics, and spatial proteomics, to identify key regulators of inflammatory and wound healing processes. I will particularly focus on the induction of different cell death types during inflammation and the impact of their removal on the inflammatory state of the environment.

Maria is a newly appointed laboratory head at WEHI, where she also completed her PhD. During her PhD (2013-2017), she investigated cytokine-induced cell death pathways. She then moved to Munich and joined Prof Matthias Mann’s lab as a Marie-Curie fellow, where she learned and applied state-of-the-art mass spectrometry to investigate cytokine signalling. Last year, Maria started her research group, which applies diverse proteomic approaches also in combination with laser microdissection to study inflammation and its resolution in vitro and in inflamed tissue.

All welcome!