WEHI Special Personalised Oncology Seminar hosted by Associate Professor Tracy Putoczki

Dr Hannah Williams

Junior Group Leader – Institute for Tissue Medicine and Pathology, University of Bern, Switzerland

Dissecting the morpho-molecular basis of epithelial plasticity in solid tumours

 

Davis Auditorium

Join via TEAMS

Including Q&A session

Epithelial plasticity is a fascinating phenomenon of tumour biology and understanding how tumour intrinsic and microenvironmental features facilitate this is important for improving patient stratification and in identifying novel treatment paradigms.

Using examples across different solid tumours this talk will explore how through the application of high and low-plex spatially resolved technologies we are able to uncover novel perspectives on transcriptional and morphological epithelial plasticity in patient tissue cohorts.

Dr Williams obtained her PhD in molecular pathology from the University of St Andrews, Scotland. She spent her first post-doc in the Wolpin-Nowak laboratory at Dana-Farber Cancer Institute, Boston where she worked on expression subtypes in pancreatic ductal adenocarcinoma. She next moved to the Le Quesne laboratory at the CRUK Scotland Institute, examining the transcriptional landscape of high-risk growth patterns in lung cancer.

Now a Junior Group Leader at the Institute for Tissue Medicine and Pathology at the University of Bern, Switzerland, her group examines the role of the extracellular matrix in epithelial plasticity utilizing spatial omics and image analysis across 2D and 3D modalities.

All Welcome!