WEHI New Medicines & Diagnostics Special Seminar hosted by Dr Rohan Volpe

Dr Dan Priebbenow
Senior Lecturer & Deputy Leader – Medicinal Chemistry Theme, Monash Institute of Pharmaceutical Sciences (MIPS) – Monash University

 

Advances in C–H Amination: New Catalytic Strategies for Chemical Synthesis

L7W Seminar Room | Bundoora Large Boardroom

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Including Q&A session

Please note this presentation will not be recorded

The transformation of inert C–H bonds into C–N bonds enables the rapid and efficient synthesis of nitrogen-containing molecules that are central to pharmaceutical, agricultural, and materials chemistry. This presentation will highlight recent work within our research group developing transition-metal catalysed nitrene transfer methods for the late-stage functionalisation of pharmaceuticals, synthesis of drug-conjugates, and post-polymerisation modification of polymer side chains. The development of new photochemical strategies that harness visible light irradiation for the mild and sustainable synthesis of valuable amine building blocks that can be readily diversified will also be presented.

Dr Dan Priebbenow completed his PhD (Organic Chemistry) at Deakin University in 2011, then was awarded an Alexander von Humboldt Postdoctoral Fellowship at RWTH Aachen University (Germany). After returning to Australia, Dan spent several years as a postdoctoral fellow in the Australian Translational Medicinal Chemistry Facility at the Monash Institute of Pharmaceutical Sciences (MIPS, Monash University). In 2020, Dan began his independent academic career at the University of Melbourne as an ARC DECRA Fellow before returning to MIPS where he is currently a Senior Lecturer in Chemistry. Dan’s research focuses on the discovery of new synthetic methods employing transition-metal catalysis and visible light irradiation that can be applied to the synthesis of new therapeutic agents, the late stage functionalisation of pharmaceuticals or the development of new tools for chemical biology.

All welcome!