WEHI Wednesday Seminar hosted by Professor Peter Czabotar
 

Dr Alisa Glukhova
Laboratory Head, Structural Biology division – New Medicines & Advanced Technologies Theme, WEHI

Lessons from cryo-EM of human 12-Lipoxygenase

 

Davis Auditorium

Join via SLIDO enter code #WEHIWednesday

Including Q&A session
 

Dr Alisa Glukhova is a laboratory head in the Structural Biology Division at WEHI and a Senior Research Fellow in the Department of Biochemistry and Pharmacology at the University of Melbourne. She earned her PhD in Chemical Biology in 2014 from the University of Michigan, where she worked on solving structures of lipid-modifying enzymes using X-ray crystallography. During her postdoctoral training in the Christopolous and Sexton/Wootten laboratories at the Monash Institute of Pharmaceutical Sciences, she used x-ray crystallography, cryo-electron microscopy, and molecular pharmacology techniques to study different G protein-coupled receptors.

Since starting her own lab in 2020, Alisa has focused on understanding the structural and biochemical aspects of the Wnt signalling pathway, an important pharmacological target for treating many cancers. Using structural biology, her team captures snapshots of different stages in the Wnt signalling cascade to understand the atomic picture and gain insights into various aspects of signal transmission through Wnt pathways. The Glukhova lab hopes to use this atomic-level information to develop better therapies for devastating human conditions, such as cancer. For her contributions to science Alisa has received a Gottschalk medal from Australian Academy of Sciences. Alisa is also a CSL Centenary Fellow.

All welcome!